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Medical condition
Nasal septum perforation
Specialty
Otorhinolaryngology
A nasal septum perforation is a medical condition in which the nasal septum, the bony/cartilaginous wall dividing the nasal cavities, develops a hole or fissure.[1]
This may be brought on directly, as in the case of nasal piercings, or indirectly, as by long-term topical drug application, including nasal administration of ethylphenidate, methamphetamine, cocaine, crushed prescription pills, or decongestant nasal sprays, chronic epistaxis, excessive nose picking and as a complication of nasal surgery like septoplasty or rhinoplasty. Much less common causes for perforated nasal septums include rare granulomatous inflammatory conditions like granulomatosis with polyangiitis. It has been reported as a side effect of anti-angiogenesis drugs like bevacizumab.
^Downs, Brian W.; Sauder, Haley M. (2023), "Septal Perforation", StatPearls, Treasure Island (FL): StatPearls Publishing, PMID 30725893, retrieved 2023-10-17
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