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In microbiology, the multiplicity of infection or MOI is the ratio of agents (e.g. phage or more generally virus, bacteria) to infection targets (e.g. cell). For example, when referring to a group of cells inoculated with virus particles, the MOI is the ratio of the number of virus particles to the number of target cells present in a defined space.[1]
^Abedon, S. T.; Bartom, E. (2013-01-01), "Multiplicity of Infection", in Maloy, Stanley; Hughes, Kelly (eds.), Brenner's Encyclopedia of Genetics (Second Edition), San Diego: Academic Press, pp. 509–510, ISBN 978-0-08-096156-9, retrieved 2022-03-09
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microbiology, the multiplicityofinfection or MOI is the ratio of agents (e.g. phage or more generally virus, bacteria) to infection targets (e.g. cell)...
at low multiplicityofinfection because at high multiplicityofinfection, all CPEs occur rapidly. Typically, the first sign of viral infections is the...
diseases caused by insects List of infectious diseases Mathematical modelling of infectious disease Multiplicityofinfection Neglected tropical diseases...
examples of specific instances where viruses need to be quantified include clone screening, multiplicityofinfection (MOI) optimization, and adaptation of methods...
λi be an eigenvalue of an n by n matrix A. The algebraic multiplicity μA(λi) of the eigenvalue is its multiplicity as a root of the characteristic polynomial...
orbit Mechanism of injury Moment of inertia, a quantification of the rotational inertia of an object Multiplicityofinfection, the ratio of infectious agents...
Microbicidal Pattern of Activation in Mycobacterium leprae-Infected Monocyte-Derived Macrophages With Low MultiplicityofInfection". Frontiers in Immunology...
into the lytic pathway. Low temperature, starvation of the cells and high multiplicityofinfection (MOI) are known to favor lysogeny (see later discussion)...
assumption of homogeneity), mutations in a given stretch of DNA after a certain amount of radiation, cells infected at a given multiplicityofinfection, bacteria...
condition in which progressive failure of the immune system allows life-threatening opportunistic infections and cancers to thrive. Without treatment...
alphaherpesvirus 2, are two members of the human Herpesviridae family, a set of viruses that produce viral infections in the majority of humans. Both HSV-1 and HSV-2...
shells and released from the cell as a result of virally induced cell lysis. Adenovirus is capable ofmultiplicity reactivation (MR) (Yamamoto and Shimojo,...
virology multiplicityofinfection (MOI) The ratio of the number of infectious agents (e.g. individual viral particles) to the number ofinfection targets...
deliver thousands of unique sgRNAs-containing vectors to a single vessel of cells by viral transduction at low multiplicityofinfection (MOI, typically...
cell (multiple infection), the infection can often succeed (multiplicity reactivation) due to reassortment of segments, provided that each of the eight genome...
DCs. With the multiplicityofinfectionof 2, approximately 1/3 of the DCs begin to express encoded SeV proteins 8 hours after infection. This proportion...
the host organism.[citation needed] Vaccinia virus is able to undergo multiplicity reactivation (MR). MR is the process by which two, or more, virus genomes...
Mistry BA, D'Orsogna MR, Chou T (June 2018). "The Effects of Statistical MultiplicityofInfection on Virus Quantification and Infectivity Assays". Biophysical...
is, multiplicity reactivation can occur.[citation needed] Upon infection, influenza virus induces a host response involving increased production of reactive...
to undergo multiplicity reactivation. That is, when polioviruses were irradiated with UV light and allowed to undergo multiple infectionsof host cells...
As they stated, multiplicity reactivation by definition involves some type of repair. Michod et al. reviewed numerous examples of MR in different viruses...
sometimes causes tumors in animals, but most often persists as a latent infection. SV40 has been widely studied as a model eukaryotic virus, leading to...
referred to as multiplicity reactivation, has been studied in lambda and T4 bacteriophages, as well as in several pathogenic viruses. In the case of pathogenic...
(May 2008). "Low multiplicityofinfection in vivo results in purifying selection against baculovirus deletion mutants". The Journal of General Virology...
the multiplicityofinfection (moi); high moi favors lysogenic pathway and low moi favors lytic pathway. The viral capsid has been the subject of studies...
of reactivation of irradiated virus (referred to as "multiplicity reactivation") immediately started a flurry of activity in the study of repair of radiation...
Brown, Christopher (October 2014). "Attenuation of virus production at high multiplicitiesofinfection in Aureococcus anophagefferens". Virology. 466–467:...
(2013-07-09). "First study of the negative binomial distribution applied to higher moments of net-charge and net-proton multiplicity distributions". Physics...
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