A multicenter research trial is a clinical trial that involves more than one independent medical institutions in enrolling and following trial participants.[1] In multicenter trials the participant institutions follow a common treatment protocol and follow the same data collection guidelines, and there is a single
coordinating center that receives, processes and analyzes study data.[2][3]
^Friedman, LM; Furberg, CD; et al. (2015). "Multicenter Trials". Fundamentals of Clinical Trials. Springer, Cham. p. 427. doi:10.1007/978-3-319-18539-2_21. ISBN 9783319185392. Retrieved 12 February 2024.
^Meinert, CL; et al. (1986). "Single-center versus multicenter trials". Clinical Trials: Design, Conduct and Analysis (Online ed.). Oxford Academic. pp. 23–29. doi:10.1093/acprof:oso/9780195035681.003.0004. ISBN 9780199864478.
^Bryant, J; et al. (2014). "Multicenter Trials: Rationale and Examples". Wiley StatsRef: Statistics Reference Online (Online ed.). Wiley. p. 1. doi:10.1002/9781118445112.stat04947. ISBN 9781118445112. Retrieved 12 February 2024.
A multicenter research trial is a clinical trial that involves more than one independent medical institutions in enrolling and following trial participants...
combined with "stratified randomization", for example by center in a multicentertrial, to "ensure good balance of participant characteristics in each group...
48-week, randomized, double-blind, double-observer, placebo-controlled multicentertrial of combination METhotrexate and intramuscular GOld therapy in rheumatoid...
RESCUE-ASDH study Official RESCUE-ASDH Trial Site is a multicenter, pragmatic, parallel group randomised trial that aims to compare the clinical and cost-effectiveness...
Lisocabtagene maraleucel's safety and efficacy were established in a multicenter clinical trial of more than 250 adults with refractory or relapsed large B-cell...
channel antagonist, has been confirmed in a prospective, observational multicentertrial of 1,250 hypertensive patients. A preparation of the two drugs is...
CAPItello-291 (NCT04305496), a randomized, double-blind, placebo-controlled, multicentertrial in 708 participants with locally advanced or metastatic HR-positive...
(2000). "Interrater reliability of the Clinical Dementia Rating in a multicentertrial". Journal of the American Geriatrics Society. 48 (5): 558–9. doi:10...
nirsevimab based on three trials, two of which were randomized, double-blind, placebo-controlled, multicenter clinical trials (Trials 03, 04 and 05). The key...
Multicenter Automatic Defibrillator Implantation Trial and MADIT II are implantable cardioverter defibrillator (or ICD) trials which investigate whether...
based on IMpassion130 (NCT02425891), a multicenter, international, double-blinded, placebo-controlled, randomized trial that included 902 participants with...
evaluated in Study JZP458-201 (NCT04145531), an open-label, multi-cohort, multicentertrial in 102 patients with acute lymphoblastic leukemia or lymphoblastic...
John Sullivan and Findlay Russell, developed clinically via multicenter clinical trials in the United States and commercialized by BTG Limited (formerly...
experimental doses of 400 mg have rendered little response. A large, multicentertrial comparing carbamazepine and lithium over two and a half years found...
M, Lucky A, Shavin J, Goldberg G, Dunlap F, et al. (July 1995). "Multicentertrial for long-term safety and efficacy comparison of 0.05% desonide and...
2023). A Phase III, Randomized, Double-Blind, Placebo-Controlled, MulticenterTrial to Evaluate the Safety and Efficacy of AMX0035 Versus Placebo for...
with a combination of amitriptyline and haloperidol--a double-blind multicentertrial". Journal of Psychiatric Research. 43 (7): 702–710. doi:10.1016/j...
1988). "Alprazolam in panic disorder and agoraphobia: results from a multicentertrial. II. Patient acceptance, side effects, and safety". Archives of General...
Efficacy was evaluated in QUILT-3.032 (NCT0302285), a single-arm, multicentertrial of 77 participants with Bacillus Calmette-Guérin-unresponsive, high-risk...
Waninger AL, Iyengar S, Wernicke JF (2005). "A double-blind, randomized multicentertrial comparing duloxetine with placebo in the management of diabetic peripheral...
cutaneous T-cell lymphoma: positive results of a randomized, controlled, multicentertrial testing the efficacy and safety of a novel mechlorethamine, 0.02%...
failure in toddlers with Turner syndrome: a randomized, controlled, multicentertrial". The Journal of Clinical Endocrinology and Metabolism. 92 (9): 3406–3416...
mafodotin was evaluated in DREAMM-2 (NCT 03525678), an open-label, multicentertrial. Participants received either belantamab mafodotin, 2.5 mg/kg or 3...
Global Information