MirGeneDB is a database of manually curated microRNA genes that have been validated and annotated by experts.
Contact
Research center
Arctic University of Norway, Science for Life Laboratory, Oslo University Hospital, Dartmouth College
Authors
Bastian Fromm & Kevin J. Peterson
Primary citation
Bastian Fromm, Eirik Høye, Diana Domanska, Xiangfu Zhong, Ernesto Aparicio-Puerta, Vladimir Ovchinnikov, Sinan U Umu, Peter J Chabot, Wenjing Kang, Morteza Aslanzadeh, Marcel Tarbier, Emilio Mármol-Sánchez, Gianvito Urgese, Morten Johansen, Eivind Hovig, Michael Hackenberg, Marc R Friedländer, Kevin J Peterson, MirGeneDB 2.1: toward a complete sampling of all major animal phyla, Nucleic Acids Research, 2021, https://doi.org/10.1093/nar/gkab1101
Release date
2015, 2020, 2021
Access
Website
http://www.mirgenedb.org/
Miscellaneous
Version
2.1
Curation policy
manual
MirGeneDB is a database of manually curated microRNA genes that have been validated and annotated as initially described in Fromm et al. 2015[1] and Fromm et al. 2020.[2] MirGeneDB 2.1[3] includes more than 16,000 microRNA gene entries representing more than 1,500 miRNA families from 75 metazoan species and published in the 2022 NAR database issue. All microRNAs can be browsed, searched and downloaded.
^Fromm, Bastian; Billipp, Tyler; Peck, Liam E.; Johansen, Morten; Tarver, James E.; King, Benjamin L.; Newcomb, James M.; Sempere, Lorenzo F.; Flatmark, Kjersti; Hovig, Eivind; Peterson, Kevin J. (2015-11-23). "A Uniform System for the Annotation of Vertebrate microRNA Genes and the Evolution of the Human microRNAome". Annual Review of Genetics. 49 (1): 213–242. doi:10.1146/annurev-genet-120213-092023. ISSN 0066-4197. PMC 4743252. PMID 26473382.
MirGeneDB is a database of manually curated microRNA genes that have been validated and annotated as initially described in Fromm et al. 2015 and Fromm...
curated miRNA gene database MirGeneDB. miRNAs are abundant in many mammalian cell types miRNAs appear to target about 60% of the genes of humans and other...
about their binding sites, or about their target genes. Examples include the following: footprintDB-- a metadatabase of multiple databases, including...
1999 (1999-10-12) 203 The 1985 search for South Carolina serial killer Larry Gene Bell. 4 (17) "Cracking the Cartel" Jeffery Fine David A. Taylor October 19...
to treat myasthenia gravis. An endogenous inhibitor of AChE in neurons is Mir-132 microRNA, which may limit inflammation in the brain by silencing the...
from this source, which is in the public domain. Loomis, D.; Richardson, D.B.; Bena, J.F.; Bailer, A.J. (2004). "Deindustrialisation and the Long Term...
resulting in increased protein expression of MEK1 and cyclin E1. By inhibiting mir-424 in normal endothelial cells they could observe the same increased protein...
Chrétien returned safely to Earth from Mir aboard Soyuz TM-6, nearly 366 days after Titov and Manarov launched to Mir aboard Soyuz TM-4. Their spacecraft...
Retrieved June 26, 2013. Rüther T (March 5, 2019). "Essen und Sprechen Geben Sie mir ein Semmelbrötchen!". Faz.net. Archived from the original on October 20,...
or for attenuation of regulation and cell-cell disassociation. The CD86 gene encodes a type I membrane protein that is a member of the immunoglobulin...
Reading Frame 66, is a 361aa protein in humans that is encoded by the CXorf66 gene. The protein encoded is predicted to be a type 1 transmembrane protein; however...
Ehlers-Danlos Syndrome". In Adam MP, Everman DB, Mirzaa GM, Pagon RA, Wallace SE, Bean LJ, et al. (eds.). GeneReviews. University of Washington, Seattle...
(mir-16, miR-34c and miR-199a). Of these miRNAs, miR-16, miR-18a, miR-21, miR-34c, miR-125b, miR-101, miR-155, miR-182, miR-185 and miR-192 are among those...
differentiation or inappropriate survival of fibroblasts.[citation needed] mir-29 microRNA precursor investigations in mice have produced reversal of induced...
NF-kappaB and miR-221. SND1 promotes migration and invasion via angiotensin II type 1 receptor and TGFβ signaling. SND1 expression is regulated by Mir-184 in...
19–36. doi:10.1111/1346-8138.16207. PMID 34709679. S2CID 240073350. Martinez-Mir A, Zlotogorski A, Gordon D, Petukhova L, Mo J, Gilliam TC, et al. (February...
377–8. doi:10.3113/FAI.2007.0377. PMID 17371662. S2CID 10787216. Martinez-Mir A, Zlotogorski A, Londono D, Gordon D, Grunn A, Uribe E, Horev L, Ruiz IM...
Dorfman DM, Wilson DB, Bruns GA, Orkin SH (1992). "Human transcription factor GATA-2. Evidence for regulation of preproendothelin-1 gene expression in endothelial...
content in genes and their respective chromosomal bands, have been used to understand functional IDP segments. IDPbyNMR DisProt database MobiDB database...