Metallothionein-2 is a metallothionein protein that in humans is encoded by the MT2A gene.[3][4]
The single-nucleotide polymorphism rs28366003 which substitutes guanine for adenine in MT2A is associated with certain cancers and some chronic diseases.[5]
^ abcGRCh38: Ensembl release 89: ENSG00000125148 – Ensembl, May 2017
^"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^Karin M, Richards RI (Dec 1982). "Human metallothionein genes--primary structure of the metallothionein-II gene and a related processed gene". Nature. 299 (5886): 797–802. Bibcode:1982Natur.299..797K. doi:10.1038/299797a0. PMID 7133118. S2CID 4332683.
^"Entrez Gene: MT2A metallothionein 2A".
^Sekovanić A, Jurasović J, Piasek M (2020). "Metallothionein 2A gene polymorphisms in relation to diseases and trace element levels in humans". Arhiv Za Higijenu Rada I Toksikologiju. 71 (1): 27–47. doi:10.2478/aiht-2020-71-3349. PMC 7837243. PMID 32597135.
and 14 Related for: Metallothionein 2A information
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suppressor gene in the esophageal carcinoma, interacts directly with metallothionein2A and links to apoptosis". Biochemical and Biophysical Research Communications...
Ordonez-Ercan D, Dasgupta P, Chellappan S (Mar 2005). "Induction of human metallothionein 1G promoter by VEGF and heavy metals: differential involvement of E2F...
This gene encodes a transcription factor that induces expression of metallothioneins and other genes involved in metal homeostasis in response to heavy...
Gedamu L, Pelletier JP (1992). "Expression of c-fos, c-jun, jun-B, metallothionein and metalloproteinase genes in human chondrocyte". FEBS Lett. 306 (2–3):...
S2CID 2490974. Iguchi K, Otsuka T, Usui S, et al. (2004). "Zinc and metallothionein levels and expression of zinc transporters in androgen-independent...
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