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Massively parallel signature sequencing information


Massive parallel signature sequencing (MPSS) is a procedure that is used to identify and quantify mRNA transcripts, resulting in data similar to serial analysis of gene expression (SAGE), although it employs a series of biochemical and sequencing steps that are substantially different.

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Massively parallel signature sequencing

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Massive parallel signature sequencing (MPSS) is a procedure that is used to identify and quantify mRNA transcripts, resulting in data similar to serial...

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DNA sequencing

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the high-throughput sequencing technologies, massively parallel signature sequencing (or MPSS, also called next generation sequencing), was developed in...

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MicroRNA sequencing

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MicroRNA sequencing (miRNA-seq), a type of RNA-Seq, is the use of next-generation sequencing or massively parallel high-throughput DNA sequencing to sequence...

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Transposon sequencing

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Transposon insertion sequencing (Tn-seq) combines transposon insertional mutagenesis with massively parallel sequencing (MPS) of the transposon insertion...

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Transcriptome

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expression (SAGE), cap analysis of gene expression (CAGE), and massively parallel signature sequencing (MPSS). The transcriptome encompasses all the ribonucleic...

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Transcriptomics technologies

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influenced by the development of high-throughput sequencing technologies. Massively parallel signature sequencing (MPSS) was an early example based on generating...

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Bioinformatics

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sequence tag (EST) sequencing, serial analysis of gene expression (SAGE) tag sequencing, massively parallel signature sequencing (MPSS), RNA-Seq, also...

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Whole genome sequencing

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Rothberg JM (2008). "The complete genome of an individual by massively parallel DNA sequencing". Nature. 452 (7189): 872–6. Bibcode:2008Natur.452..872W....

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Metagenomics

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environmental sample generated with high-throughput sequencing, in this case massively parallel pyrosequencing developed by 454 Life Sciences. Another...

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Circulating tumor DNA

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Johns Hopkins University. Safe-Seq decreases the error rate of massively parallel sequencing in order to increase the sensitivity to rare mutants. It achieves...

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Cistrome

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combined with microarray analysis "ChIP-on-chip" or with massively parallel DNA sequencing "ChIP-Seq" have greatly facilitated the definition of the...

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Environmental DNA

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when detecting sympatric taxa. Passive eDNA surveys employ massively-parallel DNA sequencing to amplify all eDNA molecules in a sample with no a priori...

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Cancer genome sequencing

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et al. (April 2008). "The complete genome of an individual by massively parallel DNA sequencing". Nature. 452 (7189): 872–6. Bibcode:2008Natur.452..872W....

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DNase I hypersensitive site

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So, they used 125 different human cell types. This way, using the massive sequencing technique, they obtained the DHSs profiles of every cellular type...

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Gustavo Stolovitzky

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Roach developed sophisticated methods for the analysis of Massively Parallel Signature Sequencing (MPSS) data. In 2008, he was a visiting scholar at the...

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Helmy Eltoukhy

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DNA sequencing. That research was funded, in part, by one of the first National Human Genome Research Institute grants awarded for massive parallel sequencing...

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COSMIC cancer database

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somatically acquired rearrangements in cancer using genome-wide massively parallel paired-end sequencing". Nature Genetics. 40 (6): 722–729. doi:10.1038/ng.128...

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Extracellular RNA

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bodily fluids. The advent of massively parallel sequencing (next-generation sequencing) lead to variations in DNA sequencing that allowed for high-throughput...

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Degradomics

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the HeLa S3 transcriptome using randomly primed cDNA and massively parallel short-read sequencing. Biotechniques 45 (1):81-94 (2008). Wang Z., Gerstein M...

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