Mass cytometry is a mass spectrometry technique based on inductively coupled plasma mass spectrometry and time of flight mass spectrometry used for the determination of the properties of cells (cytometry).[1][2] In this approach, antibodies are conjugated with isotopically pure elements, and these antibodies are used to label cellular proteins. Cells are nebulized and sent through an argon plasma, which ionizes the metal-conjugated antibodies. The metal signals are then analyzed by a time-of-flight mass spectrometer. The approach overcomes limitations of spectral overlap in flow cytometry by utilizing discrete isotopes as a reporter system instead of traditional fluorophores which have broad emission spectra.[3]
^Dmitry Bandura; Vladimir Baranov; Olga Ornatsky; Scott D. Tanner; Kinach R; Lou X; Pavlov S; Vorobiev S; Dick JE; Antonov A (2009). "Mass Cytometry: Technique for Real Time Single Cell Multitarget Immunoassay Based on Inductively Coupled Plasma Time-of-Flight Mass Spectrometry". Analytical Chemistry. 81 (16): 6813–6822. doi:10.1021/ac901049w. PMID 19601617.
^Di Palma, Serena; Bodenmiller, Bernd (2015). "Unraveling cell populations in tumors by single-cell mass cytometry". Current Opinion in Biotechnology. 31: 122–129. doi:10.1016/j.copbio.2014.07.004. ISSN 0958-1669. PMID 25123841.
^Cite error: The named reference SpitzerNolan2016 was invoked but never defined (see the help page).
Masscytometry is a mass spectrometry technique based on inductively coupled plasma mass spectrometry and time of flight mass spectrometry used for the...
Cytometry is the measurement of number and characteristics of cells. Variables that can be measured by cytometric methods include cell size, cell count...
Flow cytometry (FC) is a technique used to detect and measure the physical and chemical characteristics of a population of cells or particles. In this...
Cytometry by time of flight, or CyTOF, is an application of masscytometry used to quantify labeled targets on the surface and interior of single cells...
solutions to large-scale data management and analysis (2010) Single-cell masscytometry of differential immune and drug responses across a human hematopoietic...
Flow cytometry bioinformatics is the application of bioinformatics to flow cytometry data, which involves storing, retrieving, organizing and analyzing...
previously known as Fluidigm Corp., offers analytical masscytometry systems for flow cytometry and tissue imaging, along with associated assays and reagents...
Flow Cytometry Standard (FCS) is a data file standard for the reading and writing of data from flow cytometry experiments. The FCS specification has traditionally...
Soviet born Canadian scientist and one of the original co-inventors of Masscytometry technology... He co-founded DVS Sciences in 2004 (acquired by Fluidigm...
Canadian scientist, notable for being one of the co-inventors of the Masscytometry technology. Bandura co-founded DVS Sciences in 2004 (acquired by Fluidigm...
Quantitative MassCytometry July 2012 Human CD4+ lymphocytes for antigen quantification: Characterization using conventional flow cytometry and masscytometry Nov...
combination of heavy-metal RNA probes and protein antibodies to adapt masscytometry for multiomic analysis. In parallel to the advances in highthroughput...
p-Creode has been tested on a range of single-cell platforms, including masscytometry, multiplex immunofluorescence, and single-cell RNA-seq. No prior information...
of compensation in multiplex flow cytometry is effectively eliminated. Laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS) is a powerful...
Artery Disease: The Role of State‐of‐the‐Art Immunophenotyping With MassCytometry in the Diagnosis of Atherosclerosis". Journal of the American Heart...
Rolls Lab pioneered is the merging of DREADDs technology with CyTOyF mass-cytometry to enable the high resolution measurements of the immune system after...
Tissue image cytometry or tissue cytometry is a method of digital histopathology and combines classical digital pathology (glass slides scanning and virtual...
learning computational models of cellular signaling from single-cell masscytometry data. In 2022, Krishnaswamy's research, teaching and community work...
(1925–2000), Israeli politician Dmitry Bandura is a scientist, co-inventor of Masscytometry Charles K. Bliss (1897–1985), inventor of Blissymbols Kasper Blond (1889–1964)...
cancer, particularly colorectal cancer. Kemp uses multiplex imaging and masscytometry in her work. Kemp is part of the Maurice Wilkins Centre for Molecular...
detect dozens of proteins in a single tissue section. She used imaging masscytometry to study the immune cells found in brain lesions of MS patients. In...
Songbirds and The Bird Detective Debra W. Soh sex science writer Scott D. Tanner chemist, co-inventor of masscytometry and the collision/reaction cell...
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