Protein-coding gene in the species Homo sapiens
MZF1 Available structures PDB Human UniProt search: PDBe RCSB
Identifiers Aliases MZF1 , MZF-1, MZF1B, ZFP98, ZNF42, ZSCAN6, myeloid zinc finger 1External IDs OMIM: 194550; MGI: 107457; HomoloGene: 9633; GeneCards: MZF1; OMA:MZF1 - orthologs Gene location (Human) Chr. Chromosome 19 (human)[1] Band 19q13.43 Start 58,561,931 bp[1] End 58,573,575 bp[1]
Gene location (Mouse) Chr. Chromosome 7 (mouse)[2] Band 7 A1|7 7.73 cM Start 12,776,230 bp[2] End 12,788,691 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in pancreatic ductal cell right uterine tube right lobe of thyroid gland right hemisphere of cerebellum pituitary gland left lobe of thyroid gland anterior pituitary right adrenal gland right adrenal cortex left ovary
Top expressed in male urethra superior frontal gyrus primary visual cortex neural layer of retina dentate gyrus of hippocampal formation granule cell spermatid spermatocyte granulocyte tail of embryo embryo
More reference expression data
BioGPS More reference expression data
Gene ontology Molecular function
DNA-binding transcription activator activity, RNA polymerase II-specific
protein homodimerization activity
DNA binding
protein binding
nucleic acid binding
metal ion binding
RNA polymerase II cis-regulatory region sequence-specific DNA binding
DNA-binding transcription repressor activity, RNA polymerase II-specific
DNA-binding transcription factor activity
DNA-binding transcription factor activity, RNA polymerase II-specific
Cellular component Biological process
positive regulation of transcription by RNA polymerase II
transcription, DNA-templated
negative regulation of transcription by RNA polymerase II
regulation of transcription, DNA-templated
transcription by RNA polymerase II
Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez Ensembl UniProt RefSeq (mRNA) NM_001267033 NM_003422 NM_198055
NM_001290452 NM_001290453 NM_145819 NM_001382820 NM_016793
RefSeq (protein) NP_001253962 NP_003413 NP_932172
Location (UCSC) Chr 19: 58.56 – 58.57 Mb Chr 7: 12.78 – 12.79 Mb PubMed search [3] [4]
Wikidata View/Edit Human View/Edit Mouse
Myeloid zinc finger 1 is a protein that in humans is encoded by the MZF1 gene.[5] [6]
^ a b c GRCh38: Ensembl release 89: ENSG00000099326 – Ensembl, May 2017
^ a b c GRCm38: Ensembl release 89: ENSMUSG00000030380 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine .
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine .
^ Hromas R, Collins SJ, Hickstein D, Raskind W, Deaven LL, O'Hara P, Hagen FS, Kaushansky K (September 1991). "A retinoic acid-responsive human zinc finger gene, MZF-1, preferentially expressed in myeloid cells". J Biol Chem . 266 (22): 14183–7. doi:10.1016/S0021-9258(18)98664-3 . PMID 1860835.
^ "Entrez Gene: MZF1 myeloid zinc finger 1".
Last Update: 2024-01-05T22:16:37Z
Myeloid zinc finger 1 is a protein that in humans is encoded by the MZF1 gene. MZF1 has been shown to interact with SCAND1. In 2014, the laboratory of...
Word Count : 745
Last Update: 2023-09-23T02:10:54Z
Inferred motif from similar protein – High-throughput in vitro [570] VAAGTTT MZF1 ENSG00000099326 C2H2 ZF Known motif – In vivo/Misc source [571] DRDGGGGAD...
Word Count : 81
Last Update: 2013-03-22T19:28:39Z
Mehrzweckfahrzeug, a type of emergency land ambulance in Germany known as MZF MZF1 , a protein Yangum language, spoken in Papua New Guinea (by ISO 639 code)...
Word Count : 68
Last Update: 2023-12-03T01:46:07Z
MOBKL2A: encoding enzyme Mps one binder kinase activator-like 2A MZF1 -AS1: encoding protein MZF1 antisense RNA 1 NCLN: encoding protein Nicalin NFKBID: encoding...
Word Count : 2547
Last Update: 2024-04-30T08:47:46Z
(x2), AREB6, MZF1 (x2), ATF6, ER, and P53. This suggests that these transcription factors in particular, and especially ZKSCAN3 and MZF1 on the basis...
Word Count : 1503
Last Update: 2024-04-30T08:44:05Z
suppressor cggtgggGGAGgggcagga E2F7 Cell cycle regulator cacaggaGGGAaatata MZF1 Myeloid zinc finger 1 factors gcGGGGagcag ETSF Human and murine ETS1 factors...
Word Count : 906
Last Update: 2024-03-10T02:03:13Z
HIFF Aryl hydrocarbon receptor nuclear translocator-like, homodimer 1.000 MZF1 Myeloid zinc finger protein 0.992 STAT STAT5: signal transducer and activator...
Word Count : 1317
Last Update: 2023-08-18T12:52:36Z
protein 384 ZNF300 KRAB-containing zinc finger protein 300 MZF1 Myeloid zinc finger protein MZF1 SIX4 Sine oculis homeobox homolog 4 ETV4 ETS translocation...
Word Count : 1391
Last Update: 2023-12-05T12:18:15Z
V$AP1R MAF and AP1 related factors 1225 - 0.996 gcacggcgtcAGCAgctcggacgca V$MZF1 Myeloid zinc finger 1 factors 1040 - 0.995 agGGGGaagcg V$ZF02 C2H2 zinc finger...
Word Count : 1669
Last Update: 2023-11-28T19:35:14Z
"Characterization of the DNA-binding properties of the myeloid zinc finger protein MZF1 : two independent DNA-binding domains recognize two DNA consensus sequences...
Word Count : 2326
Last Update: 2024-03-08T20:51:29Z
limited to) EGR1, p53, E2F3, E2F4, PLAG1, NeuroD2, Myf5, IKZF1, SMAD3, KRAB, MZF1 , and c-Myb. Expression of QSER1 is seen at levels lower than 50% in many...
Word Count : 2093
Last Update: 2024-03-10T09:11:14Z
(TFIIB) recognition element 97 103 Negative 1.0 Myeloid zinc finger protein MZF1 151 161 Negative 1.0 Myelin transcription factor 1-like, neuronal C2HC zinc...
Word Count : 1913
Last Update: 2024-03-10T00:05:34Z
Detailed family information Start End Strand Myeloid zinc finger protein MZF1 286 296 + Fork head domain factors FOXK2 54 70 - X-linked zinc finger protein...
Word Count : 869
Last Update: 2024-03-22T03:42:25Z
"Characterization of the DNA-binding properties of the myeloid zinc finger protein MZF1 : two independent DNA-binding domains recognize two DNA consensus sequences...
Word Count : 1583
Last Update: 2024-03-28T02:01:26Z
highest matrix similarity (0.97~0.99) such as: Myeloid zinc finger 1 factor (MZF1 ) Nuclear factor of activated T-cells Hepatocyte nuclear factor 3 (alpha,...
Word Count : 4000
Last Update: 2023-12-12T08:31:38Z
A number of transcription factors such as FOXP1, SOX5, SOX6, SOX4, and MZF1 are likely to bind with the promoter, often acting to downregulate transcription...
Word Count : 1883
Last Update: 2024-04-03T13:48:07Z
a list of some that retain a high matrix similarity: Myeloid zinc finger MZF1 Zinc finger protein 750 FOXP1 KRAB-containing zinc finger protein 300 The...
Word Count : 1669
Last Update: 2023-11-23T19:13:26Z
generated by the ElDorado program on Genomatix: Myeloid zinc finger protein (MZF1 ) Forkhead box H1 (Foxh1) Polyomavirus enhancer A binding protein 3 (ETV4)...
Word Count : 962
Last Update: 2024-05-10T20:16:01Z
Transcription Factor Abbreviation Binding Site Strand Myeloid zinc finger protein MZF1 GTGGGGATCCG + Cyclin D binding myb-like transcription factor DMTF CACCCCTAGGCCCGA...
Word Count : 1223
Last Update: 2023-12-02T22:53:59Z
Factor Start End Strand Matrix Score Sequence Myeloid zinc finger protein MZF1 115 125 - 1.000 gtGGGGaggga Heat shock factor 2 91 115 - 0.953 aggtacctagaaAGAAaggtcagcg...
Word Count : 1399
Last Update: 2024-04-29T15:12:34Z
domain factors 35 51 + E2FF E2F-myc activator/cell cycle regulator 357 373 - MZF1 Myeloid zinc finger 1 factors 497 507 + HAND Twist subfamily of class B bHLH...
Word Count : 683
Last Update: 2022-10-17T10:52:44Z
have been described for this gene. SCAND1 has been shown to interact with MZF1 . GRCh38: Ensembl release 89: ENSG00000171222 – Ensembl, May 2017 GRCm38:...
Word Count : 674
Last Update: 2023-06-08T22:39:03Z
related transcription factor 23 35 + gcgggtGGGGatg Myeloid zinc finger protein MZF1 27 37 + gtGGGGatggc Hypermethylated in cancer 1 29 41 - gacTGCCatcccc Yin...
Word Count : 1154
Last Update: 2024-03-31T21:46:12Z
include: Fork Head Domain Factors (FKHD) Myeloid Zinc Finger 1 Factors (MZF1 ) Pleomorphic Adenoma Gene (PLAG) C2H2 Zinc Finger Transcription Factors 2...
Word Count : 1064
Last Update: 2024-03-31T11:04:01Z
polymerase II transcription factor IIB), PLAG1 (pleomorphic adenoma gene 1), MZF1 (myeloid zinc finger 1 factors), and SP1 (GC-Box factors SP1/GC). FAM89A's...
Word Count : 2102
Last Update: 2023-12-03T01:41:23Z
Sites Family Description CAAT CCAAT binding factor XBBF X-box binding factor MZF1 Myeloid zinc finger 1 factor EGRF Wilms tumor suppressor KLFS Krueppel-like...
Word Count : 1286
Last Update: 2024-05-22T03:02:27Z
819 841 (-) 1.00 Myeloid zinc finger 1 factors Myeloid zinc finger protein MZF1 1002 1012 (-) 1.00 C2H2 zinc finger transcription factors 2 KRAB-containing...
Word Count : 772