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C6orf222 is a protein that in humans is encoded by the C6orf222 gene (6p21.31).[1][2] C6orf222 is conserved in mammals, birds and reptiles with the most distant ortholog being the green sea turtle, Chelonia mydas. The C6orf222 protein contains one mammalian conserved domain: DUF3293. The protein is also predicted to contain a BH3 domain, which has predicted conservation in distant orthologs from the clade Aves.[3][4]
^NCBI Protein. "uncharacterized protein c6orf222". NCBI. Retrieved 23 January 2015.
^NCBI Gene. "C6orf222 chromosome 6 open reading frame 222 [ Homo sapiens (human) ]". NCBI. Retrieved 23 January 2015.
^NCBI BLAST. "NP_001010903:uncharacterized protein C6orf222". NCBI. Retrieved 30 January 2015.
^DeBartolo, Joe; Taipale, Mikko; Keating, Amy (June 26, 2014). "Genome-Wide Prediction and Validation of Peptides That Bind Human Prosurvival Bcl-2 Proteins". PLOS Computational Biology. 10 (6): e1003693. Bibcode:2014PLSCB..10E3693D. doi:10.1371/journal.pcbi.1003693. PMC 4072508. PMID 24967846.
C6orf222 is a protein that in humans is encoded by the C6orf222 gene (6p21.31). C6orf222 is conserved in mammals, birds and reptiles with the most distant...