List of immunofluorescence findings for autoimmune bullous conditions information
See also: List of cutaneous conditions
This is a dynamic list and may never be able to satisfy particular standards for completeness. You can help by adding missing items with reliable sources.
Several cutaneous conditions can be diagnosed with the aid of immunofluorescence studies.
Cutaneous conditions with positive direct or indirect immunofluorescence when using salt-split skin include:
Antibody isotype(s) and location of antibody deposition in immunofluorescence studies using salt-split skin for autoimmune bullous conditions targeting the basement membrane zone of the human integumentary system
Condition
Antibody isotype(s) deposited
Localization of antibody with use of salt-split skin
Antiepilegrin cicatricial pemphigoid
IgG
Dermal
Bullous lupus erythematosus
Dermal
Bullous pemphigoid
IgG
Epidermal
Cicatricial pemphigoid
IgG
Epidermal
Epidermolysis bullosa acquisita
IgG
Dermal
Linear IgA bullous dermatosis
IgA
Epidermal
Orf-induced immunobullous disease
IgG
Dermal
Pemphigoid gestationis
IgG
Epidermal
For several subtypes of pemphigus a variety of substrates are used for indirect immunofluorescence:
Substrates used in indirect immunofluorescence studies for the different pemphigus variants
Pemphigus variant
Substrate
Pemphigus foliaceous
Guinea pig esophagus
Pemphigus vulgaris
Monkey esophagus
IgA pemphigus
Cultured skin
Paraneoplastic pemphigus
Rat bladder
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