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Limbal stem cell
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Holoclar
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Limbal stem cells, also known as corneal epithelial stem cells, are unipotent stem cells located in the basal epithelial layer of the corneal limbus. They form the border between the cornea and the sclera. Characteristics of limbal stem cells include a slow turnover rate, high proliferative potential, clonogenicity, expression of stem cell markers, as well as the ability to regenerate the entire corneal epithelium. Limbal stem cell proliferation has the role of maintaining the cornea; for example, by replacing cells that are lost via tears. Additionally, these cells also prevent the conjunctival epithelial cells from migrating onto the surface of the cornea.[2]
^Cite error: The named reference Holoclar EPAR was invoked but never defined (see the help page).
^Schlötzer-Schrehardt U, Kruse FE (September 2005). "Identification and characterization of limbal stem cells". Experimental Eye Research. 81 (3): 247–264. doi:10.1016/j.exer.2005.02.016. PMID 16051216.
Limbalstemcells, also known as corneal epithelial stemcells, are unipotent stemcells located in the basal epithelial layer of the corneal limbus. They...
chronic health issues". The limbal ring is thought to contain corneal epithelium stemcells. Diseases involving a limbalstemcell deficiency are associated...
multicellular organisms, stemcells are undifferentiated or partially differentiated cells that can change into various types of cells and proliferate indefinitely...
Mesenchymal stemcells (MSCs) also known as mesenchymal stromal cells or medicinal signaling cells, are multipotent stromal cells that can differentiate...
to severe limbalstemcell deficiency (LSCD), developed by the researchers Michele De Luca and Graziella Pellegrini, was the first stemcell therapy to...
Stemcell markers are genes and their protein products used by scientists to isolate and identify stemcells. Stemcells can also be identified by functional...
Adult stemcells are undifferentiated cells, found throughout the body after development, that multiply by cell division to replenish dying cells and regenerate...
with pterygium using collagen matrix scaffold implant with autologous limbalstemcell graft. The 2013 APAO-AIOS Congress. Hyderabad, India. Campbell TG (March...
scars not related to active inflammation in the eye Corneal edema Limbalstemcell deficiency (e.g. Aniridia) Failed corneal transplants with a non-inflammatory...
CR, Chodosh J (2013). "Boston Keratoprosthesis in the Management of LimbalStemCell Failure". Copeland and Afshari's Principles and Practice of Cornea...
hepatocyte-specific cytokeratins. Cord lining EpSC show similarities to limbalstemcells in terms of expression of ABCG2, HES1 and BMI1 in addition to p63...
between the cornea and the sclera (the white of the eye). It contains limbalstemcells in its palisades of Vogt. It may be affected by cancer or aniridia...
vitality to ocular mucous membranes, Bascom Palmer faculty introduced limbalstemcell transplantation therapy, which now can prevent potentially blinding...
Renal stemcells are self-renewing, multipotent stemcells which are able to give rise to all the cell types of the kidney. It is involved in the homeostasis...
Diagnostic Microbiology. One of the patents awarded was on corneal limbalstemcell in vitro expansion for treating ocular surface disorders jointly with...
""Katie: The Science of Seeing Again", Channel 4". Centre for Sight - LimbalStemCell Deficiency | Retrieved 24 February 2013 "Third series of Bodyshockers:...
functional marker for adult limbalstemcells of the cornea. ABCB5+ cells could regrow a human cornea on a mouse with limbalstemcell deficiency (LSCD - a blindness...
transplanting T-cells capable of fighting cancer cells via cell-mediated immunity in the course of immunotherapy, or grafting stemcells to regenerate diseased...
differentiation is the process in which a stemcell changes from one type to a differentiated one. Usually, the cell changes to a more specialized type. Differentiation...
therapy producets that use epithelial stemcell cultures. They developed a culture system that creates limbalstemcell for the regeneration of corneas, which...
pluripotent stemcells develop teratoma more efficiently and faster than human embryonic stemcells regardless the site of injection". StemCells. 28 (9):...
contralateral (normal) suprabasal limbus derived in vitro expanded corneal limbalstemcells are found to be effective as amniotic membrane based expansion is...
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