Leukocyte esterase (LE) is an esterase (a type of enzyme) produced by leukocytes (white blood cells). A leukocyte esterase test (LE test) is a urine test for the presence of white blood cells and other abnormalities associated with infection.
White blood cells in the urine can indicate a urinary tract infection (UTI). Positive test results may be clinically significant in the right context. The LE test is also used to screen for gonorrhea and for amniotic fluid infections. The combination of the LE test with the urinary nitrite test provides an excellent screen for establishing the presence of a UTI. Urine test strips (dipsticks) can screen for both. A urine sample that tests positive for both nitrite and leukocyte esterase should be cultured for pathogenic bacteria.[citation needed]
"It has been proposed that the reagent strip for leukocyte esterase designed for the testing of urine (Combur test UX) could be a useful tool for diagnosing spontaneous bacterial peritonitis (SBP)."[1] Braga et al. concluded that the Combur test UX urine screening test is a very sensitive and specific method for diagnosing SBP in the ascitic fluid of cirrhotic patients who have undergone paracentesis."
^Braga LL, Souza MH, Barbosa AM, Furtado FM, Campelo PA, Araújo Filho AH (May 2006). "Diagnosis of spontaneous bacterial peritonitis in cirrhotic patients in northeastern Brazil by use of rapid urine-screening test". Sao Paulo Medical Journal. 124 (3): 141–4. doi:10.1590/s1516-31802006000300006. PMID 17119690.
and 28 Related for: Leukocyte esterase information
Leukocyteesterase (LE) is an esterase (a type of enzyme) produced by leukocytes (white blood cells). A leukocyteesterase test (LE test) is a urine test...
contain esterases. Neutrophil granulocytes are the leukocytes most commonly associated with urinary infections. A positive test for leukocyteesterase normally...
glucose, ketones, bilirubin, urobilinogen, blood, white blood cells (leukocyteesterase), protein, nitrite, pH, and specific gravity. Nitrite is reported...
urinary tract are nitrate-reducing. The leukocyteesterase test indirectly detects the presence of leukocytes (white blood cells) in urine which can be...
typical for kidney stones) or signs of infection (such as a positive leukocyteesterase or nitrite). Impaired concentrating ability or elevated urine pH (distal...
present, the predictive value goes even higher. If the patient only has leukocyteesterase or bacteria in the urine, then dysuria may suggest that the patient...
immersion field from a Gram stain of a urethral swab, or positive leukocyteesterase and/or ≥10 white blood cells per high power field of the first-void...
for the presence of urinary nitrites, white blood cells (leukocytes), or leukocyteesterase. Another test, urine microscopy, looks for the presence of...
This may be a sign of infection. However, other parameters, such as leukocyteesterase, urine white blood cell count, and symptoms such as dysuria, urinary...
their operation is based on the detection of granulocytes esterases, including leukocytes. This method, however, is burdened with a large number of false...
the anaphylatoxin C3a interacts with its C3a receptor (C3aR) to recruit leukocytes, C3b contributes to further downstream complement activation. C3b binds...
acquired resistance include the production of drug-inactivating enzymes (esterases or kinases), as well as the production of active ATP-dependent efflux...
disorder characterized by accumulation of triglycerides in the cytoplasm of leukocytes (Jordans' anomaly), muscle, liver, fibroblasts, and other tissues. It...
J, Sakr A, Lichtin JL, Bronaugh RL (August 1994). "Characterization of esterase and alcohol dehydrogenase activity in skin. Metabolism of retinyl palmitate...
demonstrate this activity; the cord factor molecules must be fully intact. Esterase activity that targets cord factor results in the lysis of M. tuberculosis...
Lichtenheld M, Podack ER (November 1988). "Characterization of three serine esterases isolated from human IL-2 activated killer cells". Journal of Immunology...
finally into the target cell cytosol. Granzymes are part of the serine esterase family. They are closely related to other immune serine proteases expressed...
immunological dysfunction", as well as haematotoxicity, resulting in a low leukocyte count. In the period of 1946 to 1963, several cases of intoxication due...
spectrum of aromas in wine are associated with glycosidases, β-glucosidases, esterases, phenolic acid decarboxylases and citrate lyases. By using molecular biology...
conditions List of genes mutated in pigmented cutaneous lesions List of human leukocyte antigen alleles associated with cutaneous conditions List of immunofluorescence...
and symptoms of acquired von Willebrand disease, angioedema due to C1-esterase inhibitor deficiency, or hepatitis C virus infection (e.g. clinical hepatitis...
(Dec 1976). "Assignment and linear order of human acid phosphatase-2, esterase A4, and lactate dehydrogenase A genes on chromosome 11". Cytogenet Cell...
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