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Laboratory mouse information


Line drawing of a laboratory mouse
The albino laboratory mouse is an iconic model organism for scientific research in a variety of fields
Albino SCID
An SCID
With intermediate coat colour
Intermediate coat colour
Kept as a pet standing on a patch of grass
Kept as a pet

The laboratory mouse or lab mouse is a small mammal of the order Rodentia which is bred and used for scientific research or feeders for certain pets. Laboratory mice are usually of the species Mus musculus. They are the most commonly used mammalian research model and are used for research in genetics, physiology, psychology, medicine and other scientific disciplines. Mice belong to the Euarchontoglires clade, which includes humans. This close relationship, the associated high homology with humans, their ease of maintenance and handling, and their high reproduction rate, make mice particularly suitable models for human-oriented research. The laboratory mouse genome has been sequenced and many mouse genes have human homologues.[1] Lab mice are sold at pet stores for snake food and can also be kept as pets.

Other mouse species sometimes used in laboratory research include two American species, the white-footed mouse (Peromyscus leucopus) and the North American deer mouse (Peromyscus maniculatus).

  1. ^ "MGI — Biology of the Laboratory Mouse". Informatics.jax.org. Retrieved 29 July 2010.

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Laboratory mouse

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The Monument to the laboratory mouse is a sculpture in Novosibirsk' Akademgorodok, Siberia, Russia. It is located in a park in front of the Institute of...

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populations near human activity. The house mouse has been domesticated as the pet or fancy mouse, and as the laboratory mouse, which is one of the most important...

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Peromyscus

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with the chevrotain or "mouse deer". They are New World mice only distantly related to the common house and laboratory mouse, Mus musculus. From this...

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Knockout mouse

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A knockout mouse, or knock-out mouse, is a genetically modified mouse (Mus musculus) in which researchers have inactivated, or "knocked out", an existing...

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Nude mouse

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A nude mouse is a laboratory mouse from a strain with a genetic mutation that causes a deteriorated or absent thymus, resulting in an inhibited immune...

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Vacanti mouse

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The Vacanti mouse was a laboratory mouse (circa 1996) who had what looked like a human ear grown on their back. The "ear" was actually an ear-shaped cartilage...

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Mouse Genome Informatics

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Mouse Genome Informatics (MGI) is a free, online database and bioinformatics resource hosted by The Jackson Laboratory, with funding by the National Human...

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Mus musculus domesticus

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domesticus, the Western European house mouse, is a subspecies of the house mouse (Mus musculus). Some laboratory mouse strains, such as C57BL/6, are domesticated...

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FVB mouse

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FVB is an albino, inbred laboratory mouse strain that is named after its susceptibility to Friend leukemia virus B. This strain was produced from mice...

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Flowers for Algernon

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year's Nebula Award for Best Novel (with Babel-17). Algernon is a laboratory mouse who has undergone surgery to increase his intelligence. The story is...

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Laboratory rat

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"Rules and Guidelines for Nomenclature of Mouse and Rat Strains". Mouse Genome Informatics. Jackson Laboratory. Retrieved 5 December 2018. "Outbred Stocks"...

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Oncomouse

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The OncoMouse or Harvard mouse is a type of laboratory mouse (Mus musculus) that has been genetically modified using modifications designed by Philip Leder...

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The mdx mouse is a popular model for studying Duchenne muscular dystrophy (DMD). The mdx mouse has a point mutation in its DMD gene, changing the amino...

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accept them. Similarly, a Frontiers in Oncology paper discussing a laboratory mouse dying of lymphoma after being injected with the Pfizer–BioNTech COVID-19...

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eukaryotic model organisms. During the same time period, studies on mouse genetics in the laboratory of William Ernest Castle in collaboration with Abbie Lathrop...

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Shiverer mouse

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within the myelin basic protein gene created the dysmyelinating shiverer mouse mutation". Proc Natl Acad Sci U S A. 83 (19): 7542–7546. Bibcode:1986PNAS...

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NOD mice

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a sterile environment. The incidence of spontaneous diabetes in the NOD mouse is 60–80% in females and 20–30% in males. Onset of diabetes also varies...

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Spiny mouse

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menstruation and reproductive disorders, as Mus musculus, the common laboratory mouse, does not menstruate. Captive housing of spiny mice in the mid-1960s...

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Mouse

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A mouse (pl.: mice) is a small rodent. Characteristically, mice are known to have a pointed snout, small rounded ears, a body-length scaly tail, and a...

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Fancy mouse

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A fancy mouse is a domesticated form of the house mouse (Mus musculus), one of many species of mice, usually kept as a type of pocket pet. Fancy mice...

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Domestic mouse

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Domestic mouse may refer to: Fancy mouse, domesticated mice kept as pets Laboratory mouse, domesticated mice used in scientific research Mus musculus domesticus...

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Inbred strain

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"Multiple Factor Inheritance". In Green EL (ed.). Biology of the Laboratory Mouse. New York: McGraw-Hill. p. 156. LCCN 65-27978. Lyon MF (1981). "Rules...

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encephalitis. Murine coronavirus is an important pathogen in the laboratory mouse and the laboratory rat. It is the most studied coronavirus in animals other...

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Jackson Laboratory

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education for the global biomedical community." The laboratory also provides more than 13,000 strains of mouse models to more than 2,400 organizations in 68...

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