LYL1 information

LYL1
Identifiers
Aliases	LYL1, bHLHa18, lymphoblastic leukemia associated hematopoiesis regulator 1, basic helix-loop-helix family member, LYL1 basic helix-loop-helix family member
External IDs	OMIM: 151440 MGI: 96891 HomoloGene: 4078 GeneCards: LYL1
Gene location (Human)
Chr.	Chromosome 19 (human)
End	13,103,161 bp
Gene location (Mouse)
Chr.	Chromosome 8 (mouse)
End	85,431,569 bp
RNA expression pattern
	Top expressed in
	blood; ; monocyte; ; trabecular bone; ; bone marrow; ; spleen; ; bone marrow cells; ; vena cava; ; superficial temporal artery; ; lymph node; ; appendix;
	Top expressed in
	spleen; ; bone marrow; ; blood; ; interventricular septum; ; endocardial cushion; ; yolk sac; ; internal carotid artery; ; female urethra; ; subcutaneous adipose tissue; ; ankle;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	DNA binding; RNA polymerase II transcription regulatory region sequence-specific DNA binding; protein binding; protein dimerization activity; DNA-binding transcription factor activity, RNA polymerase II-specific;
Cellular component	nucleus;
Biological process	positive regulation of transcription, DNA-templated; B cell differentiation; definitive hemopoiesis; regulation of transcription, DNA-templated; transcription, DNA-templated; blood vessel maturation; regulation of transcription by RNA polymerase II;
	Sources:Amigo / QuickGO
Orthologs
	4066
	17095
	ENSG00000104903
	ENSMUSG00000034041
	P12980
	P27792
	NM_005583
	NM_008535
	NP_005574
	NP_032561
	Wikidata
View/Edit Human	View/Edit Mouse

Protein lyl-1 is a protein that in humans is encoded by the LYL1 gene.^[5]^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000104903 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000034041 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Mellentin JD, Smith SD, Cleary ML (July 1989). "lyl-1, a novel gene altered by chromosomal translocation in T cell leukemia, codes for a protein with a helix-loop-helix DNA binding motif". Cell. 58 (1): 77–83. doi:10.1016/0092-8674(89)90404-2. PMID 2752424. S2CID 24737263.
^ "Entrez Gene: LYL1 lymphoblastic leukemia derived sequence 1".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000104903 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000034041 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid2752424-5] Mellentin JD, Smith SD, Cleary ML (July 1989). "lyl-1, a novel gene altered by chromosomal translocation in T cell leukemia, codes for a protein with a helix-loop-helix DNA binding motif". Cell. 58 (1): 77–83. doi:10.1016/0092-8674(89)90404-2. PMID 2752424. S2CID 24737263.

[entrez-6] "Entrez Gene: LYL1 lymphoblastic leukemia derived sequence 1".

LYL1 information

and 24 Related for: LYL1 information

LYL1

Myc

Homeobox

Zinc finger

Nuclear receptor

Acute lymphoblastic leukemia

List of human transcription factors

Sigma factor

Hormone receptor

NFE2L2

HES3

FOXP2

HIF1A

CREB

FOXP3

FHAD1

STAT3

Retinoid receptor

STAT protein

Estrogen receptor alpha

Progesterone receptor A

Mineralocorticoid receptor

ELF1

ATBF1