Protein-coding gene in humans
ZFHX3 Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2DA1, 2DA2, 2DA3
Identifiers Aliases ZFHX3 , ATBF1, ATBT, ZNF927, zinc finger homeobox 3External IDs OMIM: 104155; MGI: 99948; HomoloGene: 21366; GeneCards: ZFHX3; OMA:ZFHX3 - orthologs Gene location (Human) Chr. Chromosome 16 (human)[1] Band 16q22.2-q22.3 Start 72,782,885 bp[1] End 73,891,871 bp[1]
Gene location (Mouse) Chr. Chromosome 8 (mouse)[2] Band 8|8 D3 Start 108,669,276 bp[2] End 109,688,262 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in saphenous vein buccal mucosa cell synovial joint tendon of biceps brachii lateral nuclear group of thalamus pericardium urethra mucosa of paranasal sinus trigeminal ganglion spinal ganglia
Top expressed in ascending aorta aortic valve external carotid artery lacrimal gland internal carotid artery tunica media of zone of aorta vestibular membrane of cochlear duct ciliary body superior cervical ganglion lumbar spinal ganglion
More reference expression data
BioGPS More reference expression data
Gene ontology Molecular function
DNA binding
sequence-specific DNA binding
DNA-binding transcription factor activity
zinc ion binding
metal ion binding
core promoter sequence-specific DNA binding
protein binding
nucleic acid binding
enzyme binding
transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
RNA polymerase II cis-regulatory region sequence-specific DNA binding
DNA-binding transcription repressor activity, RNA polymerase II-specific
DNA-binding transcription factor activity, RNA polymerase II-specific Cellular component
cytoplasm
nuclear body
transcription regulator complex
nucleus
nucleoplasm Biological process
negative regulation of myoblast differentiation
regulation of transcription, DNA-templated
regulation of locomotor rhythm
muscle organ development
transcription by RNA polymerase II
circadian regulation of gene expression
transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of myoblast differentiation
negative regulation of transcription, DNA-templated
response to transforming growth factor beta
negative regulation of transcription by RNA polymerase II
brain development
regulation of neuron differentiation
positive regulation of cell adhesion
positive regulation of transcription by RNA polymerase II Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez Ensembl UniProt RefSeq (mRNA) RefSeq (protein) Location (UCSC) Chr 16: 72.78 – 73.89 Mb Chr 8: 108.67 – 109.69 Mb PubMed search [3] [4]
Wikidata View/Edit Human View/Edit Mouse
Zinc finger homeobox protein 3 is a protein that in humans is encoded by the ZFHX3 gene.[5] [6] [7]
^ a b c GRCh38: Ensembl release 89: ENSG00000140836 – Ensembl, May 2017
^ a b c GRCm38: Ensembl release 89: ENSMUSG00000038872 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine . ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine . ^ Morinaga T, Yasuda H, Hashimoto T, Higashio K, Tamaoki T (Dec 1991). "A human alpha-fetoprotein enhancer-binding protein, ATBF1, contains four homeodomains and seventeen zinc fingers". Mol Cell Biol . 11 (12): 6041–9. doi:10.1128/MCB.11.12.6041. PMC 361769 . PMID 1719379. ^ Miura Y, Tam T, Ido A, Morinaga T, Miki T, Hashimoto T, Tamaoki T (Dec 1995). "Cloning and characterization of an ATBF1 isoform that expresses in a neuronal differentiation-dependent manner". J Biol Chem . 270 (45): 26840–8. doi:10.1074/jbc.270.45.26840 . PMID 7592926. ^ "Entrez Gene: ATBF1 AT-binding transcription factor 1".
Last Update: 2023-11-08T04:10:52Z
"Entrez Gene: ATBF1 AT-binding transcription factor 1". Yamada K, Miura Y, Scheidl T, et al. (1996). "Assignment of the human ATBF1 transcription factor...
Word Count : 842
Last Update: 2024-04-01T17:00:44Z
factors TFIIA TFIIB TFIID TFIIE 1 2 TFIIF 1 2 TFIIH 1 2 4 2I 3A 3C1 3C2 ATBF1 BCL 6 11A 11B CTCF E4F1 EGR 1 2 3 4 ERV3 GFI1 GLI family 1 2 3 REST S1 S2...
Word Count : 4469
Last Update: 2024-06-10T15:24:43Z
factors TFIIA TFIIB TFIID TFIIE 1 2 TFIIF 1 2 TFIIH 1 2 4 2I 3A 3C1 3C2 ATBF1 BCL 6 11A 11B CTCF E4F1 EGR 1 2 3 4 ERV3 GFI1 GLI family 1 2 3 REST S1 S2...
Word Count : 4825
Last Update: 2024-06-03T07:06:15Z
factors TFIIA TFIIB TFIID TFIIE 1 2 TFIIF 1 2 TFIIH 1 2 4 2I 3A 3C1 3C2 ATBF1 BCL 6 11A 11B CTCF E4F1 EGR 1 2 3 4 ERV3 GFI1 GLI family 1 2 3 REST S1 S2...
Word Count : 8023
Last Update: 2024-05-15T18:15:20Z
factors TFIIA TFIIB TFIID TFIIE 1 2 TFIIF 1 2 TFIIH 1 2 4 2I 3A 3C1 3C2 ATBF1 BCL 6 11A 11B CTCF E4F1 EGR 1 2 3 4 ERV3 GFI1 GLI family 1 2 3 REST S1 S2...
Word Count : 6709
Last Update: 2024-06-15T23:36:36Z
factors TFIIA TFIIB TFIID TFIIE 1 2 TFIIF 1 2 TFIIH 1 2 4 2I 3A 3C1 3C2 ATBF1 BCL 6 11A 11B CTCF E4F1 EGR 1 2 3 4 ERV3 GFI1 GLI family 1 2 3 REST S1 S2...
Word Count : 1438
Last Update: 2024-04-13T08:04:48Z
factors TFIIA TFIIB TFIID TFIIE 1 2 TFIIF 1 2 TFIIH 1 2 4 2I 3A 3C1 3C2 ATBF1 BCL 6 11A 11B CTCF E4F1 EGR 1 2 3 4 ERV3 GFI1 GLI family 1 2 3 REST S1 S2...
Word Count : 2243
Last Update: 2024-06-10T18:28:27Z
factors TFIIA TFIIB TFIID TFIIE 1 2 TFIIF 1 2 TFIIH 1 2 4 2I 3A 3C1 3C2 ATBF1 BCL 6 11A 11B CTCF E4F1 EGR 1 2 3 4 ERV3 GFI1 GLI family 1 2 3 REST S1 S2...
Word Count : 13103
Last Update: 2024-06-06T11:17:10Z
factors TFIIA TFIIB TFIID TFIIE 1 2 TFIIF 1 2 TFIIH 1 2 4 2I 3A 3C1 3C2 ATBF1 BCL 6 11A 11B CTCF E4F1 EGR 1 2 3 4 ERV3 GFI1 GLI family 1 2 3 REST S1 S2...
Word Count : 3820
Last Update: 2024-05-31T02:09:45Z
factors TFIIA TFIIB TFIID TFIIE 1 2 TFIIF 1 2 TFIIH 1 2 4 2I 3A 3C1 3C2 ATBF1 BCL 6 11A 11B CTCF E4F1 EGR 1 2 3 4 ERV3 GFI1 GLI family 1 2 3 REST S1 S2...
Word Count : 9673
Last Update: 2024-03-30T10:08:41Z
factors TFIIA TFIIB TFIID TFIIE 1 2 TFIIF 1 2 TFIIH 1 2 4 2I 3A 3C1 3C2 ATBF1 BCL 6 11A 11B CTCF E4F1 EGR 1 2 3 4 ERV3 GFI1 GLI family 1 2 3 REST S1 S2...
Word Count : 5880
Last Update: 2024-06-10T18:16:58Z
factors TFIIA TFIIB TFIID TFIIE 1 2 TFIIF 1 2 TFIIH 1 2 4 2I 3A 3C1 3C2 ATBF1 BCL 6 11A 11B CTCF E4F1 EGR 1 2 3 4 ERV3 GFI1 GLI family 1 2 3 REST S1 S2...
Word Count : 9500
Last Update: 2024-05-31T05:46:50Z
factors TFIIA TFIIB TFIID TFIIE 1 2 TFIIF 1 2 TFIIH 1 2 4 2I 3A 3C1 3C2 ATBF1 BCL 6 11A 11B CTCF E4F1 EGR 1 2 3 4 ERV3 GFI1 GLI family 1 2 3 REST S1 S2...
Word Count : 6675
Last Update: 2024-01-06T04:48:58Z
factors TFIIA TFIIB TFIID TFIIE 1 2 TFIIF 1 2 TFIIH 1 2 4 2I 3A 3C1 3C2 ATBF1 BCL 6 11A 11B CTCF E4F1 EGR 1 2 3 4 ERV3 GFI1 GLI family 1 2 3 REST S1 S2...
Word Count : 2042
Last Update: 2022-10-13T20:36:36Z
factors TFIIA TFIIB TFIID TFIIE 1 2 TFIIF 1 2 TFIIH 1 2 4 2I 3A 3C1 3C2 ATBF1 BCL 6 11A 11B CTCF E4F1 EGR 1 2 3 4 ERV3 GFI1 GLI family 1 2 3 REST S1 S2...
Word Count : 1880
Last Update: 2024-04-15T20:56:49Z
factors TFIIA TFIIB TFIID TFIIE 1 2 TFIIF 1 2 TFIIH 1 2 4 2I 3A 3C1 3C2 ATBF1 BCL 6 11A 11B CTCF E4F1 EGR 1 2 3 4 ERV3 GFI1 GLI family 1 2 3 REST S1 S2...
Word Count : 4034
Last Update: 2024-05-26T23:45:53Z
factors TFIIA TFIIB TFIID TFIIE 1 2 TFIIF 1 2 TFIIH 1 2 4 2I 3A 3C1 3C2 ATBF1 BCL 6 11A 11B CTCF E4F1 EGR 1 2 3 4 ERV3 GFI1 GLI family 1 2 3 REST S1 S2...
Word Count : 7187
Last Update: 2023-08-28T20:08:46Z
factors TFIIA TFIIB TFIID TFIIE 1 2 TFIIF 1 2 TFIIH 1 2 4 2I 3A 3C1 3C2 ATBF1 BCL 6 11A 11B CTCF E4F1 EGR 1 2 3 4 ERV3 GFI1 GLI family 1 2 3 REST S1 S2...
Word Count : 1317
Last Update: 2023-12-08T19:48:13Z
factors TFIIA TFIIB TFIID TFIIE 1 2 TFIIF 1 2 TFIIH 1 2 4 2I 3A 3C1 3C2 ATBF1 BCL 6 11A 11B CTCF E4F1 EGR 1 2 3 4 ERV3 GFI1 GLI family 1 2 3 REST S1 S2...
Word Count : 2716
Last Update: 2024-02-19T19:08:01Z
factors TFIIA TFIIB TFIID TFIIE 1 2 TFIIF 1 2 TFIIH 1 2 4 2I 3A 3C1 3C2 ATBF1 BCL 6 11A 11B CTCF E4F1 EGR 1 2 3 4 ERV3 GFI1 GLI family 1 2 3 REST S1 S2...
Word Count : 2796
Last Update: 2021-09-24T13:29:16Z
factors TFIIA TFIIB TFIID TFIIE 1 2 TFIIF 1 2 TFIIH 1 2 4 2I 3A 3C1 3C2 ATBF1 BCL 6 11A 11B CTCF E4F1 EGR 1 2 3 4 ERV3 GFI1 GLI family 1 2 3 REST S1 S2...
Word Count : 1927
Last Update: 2024-04-18T00:25:38Z
factors TFIIA TFIIB TFIID TFIIE 1 2 TFIIF 1 2 TFIIH 1 2 4 2I 3A 3C1 3C2 ATBF1 BCL 6 11A 11B CTCF E4F1 EGR 1 2 3 4 ERV3 GFI1 GLI family 1 2 3 REST S1 S2...
Word Count : 6534
Last Update: 2024-02-13T23:16:58Z
factors TFIIA TFIIB TFIID TFIIE 1 2 TFIIF 1 2 TFIIH 1 2 4 2I 3A 3C1 3C2 ATBF1 BCL 6 11A 11B CTCF E4F1 EGR 1 2 3 4 ERV3 GFI1 GLI family 1 2 3 REST S1 S2...
Word Count : 2688
Last Update: 2023-08-18T23:04:22Z
factors TFIIA TFIIB TFIID TFIIE 1 2 TFIIF 1 2 TFIIH 1 2 4 2I 3A 3C1 3C2 ATBF1 BCL 6 11A 11B CTCF E4F1 EGR 1 2 3 4 ERV3 GFI1 GLI family 1 2 3 REST S1 S2...
Word Count : 874
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