LMO7 information

LMO7
Available structures
PDB	Human UniProt search: PDBe RCSB
List of PDB id codes
	2EAQ
Identifiers
Aliases	LMO7, FBX20, FBXO20, LOMP, LIM domain 7, LMO7b
External IDs	OMIM: 604362; MGI: 1353586; HomoloGene: 83924; GeneCards: LMO7; OMA:LMO7 - orthologs
Gene location (Human)
Chr.	Chromosome 13 (human)
End	75,859,870 bp
Gene location (Mouse)
Chr.	Chromosome 14 (mouse)
End	101,934,710 bp
RNA expression pattern
	Top expressed in
	sural nerve; ; right lung; ; upper lobe of left lung; ; Achilles tendon; ; left lobe of thyroid gland; ; right lobe of thyroid gland; ; stromal cell of endometrium; ; left ventricle; ; gastrocnemius muscle; ; minor salivary glands;
	Top expressed in
	secondary oocyte; ; corneal stroma; ; interventricular septum; ; left lung lobe; ; conjunctival fornix; ; right lung lobe; ; olfactory tubercle; ; atrium; ; right ventricle; ; extraocular muscle;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	metal ion binding; ubiquitin-protein transferase activity; DNA-binding transcription factor activity;
Cellular component	cytoplasm; ubiquitin ligase complex; nucleus; focal adhesion; cytosol; nuclear envelope; cell surface; apical plasma membrane;
Biological process	regulation of cell adhesion; protein ubiquitination; regulation of signaling; protein polyubiquitination; post-translational protein modification; positive regulation of transcription by RNA polymerase II;
	Sources:Amigo / QuickGO
Orthologs
	4008
	380928
	ENSG00000136153
	ENSMUSG00000033060
	Q8WWI1
	n/a
	NM_001306080; NM_005358; NM_015842; NM_015843; NM_001330583
	NM_201529; NM_001347628
NP_001293009; NP_001317512; NP_005349; NP_056667; NP_001353561;
	NP_001353562; NP_001353563; NP_001353565; NP_001293009.1
	n/a
	Wikidata
View/Edit Human	View/Edit Mouse

LIM domain only protein 7 is a protein that in humans is encoded by the LMO7 gene.^[5]^[6]^[7]

This gene encodes a protein containing a calponin homology (CH) domain, a PDZ domain, and a LIM domain. An F-box (FBX) domain is present in alternative splice variants. Members of the LIM protein family carry the LIM domain, a unique cysteine-rich zinc-binding domain. Members of the FBX protein family are involved in protein-protein interactions. The encoded protein may be involved in protein-protein interactions. Multiple alternative splice variants have been described but their full-length sequences have not been determined.^[7]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000136153 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000033060 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Putilina T, Jaworski C, Gentleman S, McDonald B, Kadiri M, Wong P (Dec 1998). "Analysis of a human cDNA containing a tissue-specific alternatively spliced LIM domain". Biochem Biophys Res Commun. 252 (2): 433–9. doi:10.1006/bbrc.1998.9656. PMID 9826547.
^ Cenciarelli C, Chiaur DS, Guardavaccaro D, Parks W, Vidal M, Pagano M (Dec 1999). "Identification of a family of human F-box proteins". Curr Biol. 9 (20): 1177–9. Bibcode:1999CBio....9.1177C. doi:10.1016/S0960-9822(00)80020-2. PMID 10531035.
^ ^a ^b "Entrez Gene: LMO7 LIM domain 7".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000136153 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000033060 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid9826547-5] Putilina T, Jaworski C, Gentleman S, McDonald B, Kadiri M, Wong P (Dec 1998). "Analysis of a human cDNA containing a tissue-specific alternatively spliced LIM domain". Biochem Biophys Res Commun. 252 (2): 433–9. doi:10.1006/bbrc.1998.9656. PMID 9826547.

[pmid10531035-6] Cenciarelli C, Chiaur DS, Guardavaccaro D, Parks W, Vidal M, Pagano M (Dec 1999). "Identification of a family of human F-box proteins". Curr Biol. 9 (20): 1177–9. Bibcode:1999CBio....9.1177C. doi:10.1016/S0960-9822(00)80020-2. PMID 10531035.

[entrez-7] "Entrez Gene: LMO7 LIM domain 7".

LMO7 information

and 5 Related for: LMO7 information

LMO7

PDZ domain

Circular RNA

Calponin homology domain

LIM domain