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Inner ear regeneration information


Inner ear regeneration is the biological process by which the hair cells and supporting cells (i.e. Hensen's cells and Deiters cells) of the ear proliferate (cell proliferation) and regrow after hair cell injury. This process depends on communication between supporting cells and the brain. Because of the volatility of the inner ear's hair cells, regeneration is crucial to the functioning of the inner ear. It is also a limited process, which contributes to the irreversibility of hearing loss in humans and other mammals.

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Inner ear regeneration

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Inner ear regeneration is the biological process by which the hair cells and supporting cells (i.e. Hensen's cells and Deiters cells) of the ear proliferate...

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Hair cell

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and inner hair cells. Damage to these hair cells results in decreased hearing sensitivity, and because the inner ear hair cells cannot regenerate, this...

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Regeneration in humans

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Regeneration in humans is the regrowth of lost tissues or organs in response to injury. This is in contrast to wound healing, or partial regeneration...

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Presbycusis

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resulting from degeneration of the cochlea or associated structures of the inner ear or auditory nerves. The hearing loss is most marked at higher frequencies...

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Auditory system

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oval window, which vibrates the perilymph liquid (present throughout the inner ear) and causes the round window to bulb out as the oval window bulges in...

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Organ of Corti

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potential. Transduction occurs through vibrations of structures in the inner ear causing displacement of cochlear fluid and movement of hair cells at the...

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Sensorineural hearing loss

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(SNHL) is a type of hearing loss in which the root cause lies in the inner ear, sensory organ (cochlea and associated structures), or the vestibulocochlear...

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Listener fatigue

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stereocilia (hair cells) of the inner ear can become subjected to bending from loud noises. Because they are not regeneratable in humans, any major damage...

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Neural encoding of sound

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micro-mechanical and neural complexities that surrounds the inner ear hair cells, artificial regeneration in vitro remains a distant reality. Recent studies suggest...

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Hearing Health Foundation

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scientists working collaboratively on scientific research towards inner ear hair cell regeneration and accelerate the time frame for developing a cure for hearing...

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Sense of balance

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number of sensory systems working together; the eyes (visual system), the inner ears (vestibular system), and the body's sense of where it is in space (proprioception)...

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Creatine kinase

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hair cells of the inner ear, spermatozoa and smooth muscle, PCr serves as an energy reservoir for the rapid buffering and regeneration of ATP in situ, as...

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Neurosphere

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nerve regeneration Researchers are exploring the use of neural stem cells (NSCs) obtained from neurospheres to aid in the regrowth of inner ear neurons...

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Glossary of medicine

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ear and the inner ear. The outer ear consists of the pinna and the ear canal. Since the outer ear is the only visible portion of the ear in most animals...

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Mandible

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movable bone of the skull (discounting the vibrating ossicles of the middle ear). It is connected to the skull's temporal bones by the temporomandibular...

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Ototoxic medication

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Ototoxicity is defined as the toxic effect on the functioning of the inner ear, which may lead to temporary or permanent hearing loss (cochleotoxic) and...

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Ototoxicity

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the inner ear. It is the snail-shaped shell containing several nerve endings that makes hearing possible. Ototoxicity typically results when the inner ear...

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Cranial neural crest

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skeletal muscles of the eye. Into the otic placode and participates in the inner ear development. Sensory ganglia of the fifth, seventh, ninth and tenth cranial...

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Reptile

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the ear; the outer ear that directs sound waves into the ear canal, the middle ear that transmits incoming sound waves to the inner ear, and the inner ear...

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Scar

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off regeneration of tissues. Another form is atrophic scarring (sunken scarring), which also has an overexpression of collagen blocking regeneration. This...

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Rib cage

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cartilage, containing a source of progenitor stem cells required for rib regeneration. The position of ribs can be permanently altered by a form of body modification...

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Hearing loss

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2013-01-22. Ander D. "Drug may reverse permanent deafness by regenerating cells of inner ear: Harvard study". National Post. Archived from the original...

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Edwin Rubel

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auditory brainstem, damage and regeneration of hair cells and protection of the mechanosensory cells in the inner ear for hearing and balance. Auditory...

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Sense

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humans, including the vestibular system (sense of balance) sensed by the inner ear and providing the perception of spatial orientation; proprioception (body...

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Basilar papilla

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the spring peeper. The basilar papilla units that are located in the inner ear of the female are tuned between 2100 and 3700 Hz. Low frequency calls...

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Liver

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true regeneration where both original function and form are restored. In some other species, such as zebrafish, the liver undergoes true regeneration by...

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