Indolent lymphoma, also known as low-grade lymphoma, is a group of slow-growing non-Hodgkin lymphomas (NHLs).[3] Because they spread slowly, they tend to have fewer signs and symptoms when first diagnosed and may not require immediate treatment. Symptoms can include swollen but painless lymph nodes, unexplained fever, and unintended weight loss.[2]
There are several subtypes, the most common of which is follicular lymphoma. Others include cutaneous T-cell lymphoma, marginal zone lymphoma, chronic lymphocytic leukemia, and Waldenström macroglobulinemia.[2]
Indolent lymphoma accounts for 41 percent of all non-Hodgkin lymphoma cases in North America and Northern Europe. It mainly affects older adults, and affects men and women almost equally.[4] White people have higher incidence rates than black and Asian people,[5] but the cause of these disparities is poorly understood.[5]
Indolent lymphoma is usually considered incurable without the use of allogeneic stem cell transplantation, unless the disease is localised. However, due to its slow-growing nature and response to treatment, patients often have prolonged survival.[5]
^Cite error: The named reference :15 was invoked but never defined (see the help page).
^ abc"Adult Non-Hodgkin Lymphoma Treatment (PDQ®)–Patient Version". National Cancer Institute. 2019-11-29. Retrieved 2020-02-03.
^"NCI Dictionary of Cancer Terms". National Cancer Institute. 2011-02-02. Retrieved 2020-02-03.
^PhD, Ines Martins (2016-02-02). "Indolent Lymphoma: What You Need to Know". Lymphoma News Today. Retrieved 2020-02-08.
^ abcLunning, Matthew; Vose, Julie M. (2012). "Management of Indolent Lymphoma: Where Are We Now and Where Are We Going". Blood Reviews. 26 (6): 279–288. doi:10.1016/j.blre.2012.09.004. ISSN 0268-960X. PMC 3632507. PMID 23063143.
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