"IgM" redirects here. For articles with topics often written as "IGM", see IGM.
Immunoglobulin M
(pentamer)
Protein type
antibody
Subunit name
Gene
Chromosomal locus
Immunoglobulin heavy chain µ
IGH@
Immunoglobulin M (IgM) is the largest of several isotypes of antibodies (also known as immunoglobulin) that are produced by vertebrates. IgM is the first antibody to appear in the response to initial exposure to an antigen;[1][2] causing it to also be called an acute phase antibody. In humans and other mammals that have been studied, plasmablasts in the spleen are the main source of specific IgM production.[3][4]
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"Immunoglobulin M". The American Heritage Dictionary of the English Language (Fourth ed.). Houghton Mifflin Company. 2004. ISBN 978-0618082308.
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Alberts, B.; Johnson, A.; Lewis, J.; Walter, P.; Raff, M.; Roberts, K. (2002). "Chapter 24". Molecular Biology of the Cell (4th ed.). Routledge. ISBN 978-0-8153-3288-6.
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Capolunghi, F.; Rosado, M. M.; Sinibaldi, M.; Aranburu, A.; Carsetti, R. (2013). "Why do we need IgM memory B cells?". Immunology Letters. 152 (2): 114–20. doi:10.1016/j.imlet.2013.04.007. PMID 23660557.
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Williams, N.; O'Connell, P. R. (2008). "Chapter 62". Bailey & Love's Short Practice of Surgery (25th ed.). CRC Press. p. 1102. ISBN 9780340939321.
ImmunoglobulinM (IgM) is the largest of several isotypes of antibodies (also known as immunoglobulin) that are produced by vertebrates. IgM is the first...
An antibody (Ab) is the secreted form of a B cell receptor; the term immunoglobulin (Ig) can refer to either the membrane-bound form or the secreted form...
Immunoglobulin therapy is the use of a mixture of antibodies (normal human immunoglobulin or NHIG) to treat several health conditions. These conditions...
facilitates the transcytosis of the soluble polymeric isoforms of immunoglobulin A and immunoglobulinM (pIg) and immune complexes. pIgRs are mainly located on...
Immunoglobulin A (Ig A, also referred to as sIgA in its secretory form) is an antibody that plays a role in the immune function of mucous membranes. The...
Immunoglobulin G (IgG) is a type of antibody. Representing approximately 75% of serum antibodies in humans, IgG is the most common type of antibody found...
"Disulfide bond assignment in human J chain and its covalent pairing with immunoglobulinM". Biochemistry. 31 (50): 12643–12647. doi:10.1021/bi00165a014. PMID 1472500...
Immunoglobulin Y (abbreviated as IgY) is a type of immunoglobulin which is the major antibody in bird, reptile, and lungfish blood. It is also found in...
immunoglobulinM deficiency is a poorly defined dysgammaglobulinemia characterized by decreased levels of IgM while levels of other immunoglobulins are...
experience severe immunosuppression. This syndrome is also known as immunoglobulin class switch recombination (Ig-CSR) deficiencies. The most common causes...
mechanism that changes a B cell's production of immunoglobulin from one type to another, such as from the isotype IgM to the isotype IgG. During this process...
hypergammaglobulinemias are caused by an excess of immunoglobulinM (IgM), because this is the default immunoglobulin type prior to class switching. Some types...
The immunoglobulin superfamily (IgSF) is a large protein superfamily of cell surface and soluble proteins that are involved in the recognition, binding...
Oligoclonal bands (OCBs) are bands of immunoglobulins that are seen when a patient's blood serum, or cerebrospinal fluid (CSF) is analyzed. They are used...
IgM nephropathy or immunoglobulinM nephropathy (IgMN) is a kind of idiopathic glomerulonephritis that is marked by IgM diffuse deposits in the glomerular...
expensive. Nontreponemal tests (NTT) measure levels of immunoglobulin G (IgG) and immunoglobulinM (IgM) antibodies produced by the host in response to lipoidal...
types of antibody: immunoglobulin A, immunoglobulin D, immunoglobulin E, immunoglobulin G, and immunoglobulinM. Each immunoglobulin class differs in its...
The immunoglobulin light chain is the small polypeptide subunit of an antibody (immunoglobulin). A typical antibody is composed of two immunoglobulin (Ig)...
called IgM. IgD is also produced in a secreted form that is found in very small amounts in blood serum, representing 0.25% of immunoglobulins in serum...
of IgM and IgD.: 84 ImmunoglobulinM deficiency ImmunoglobulinM Skin lesion List of cutaneous conditions "X-linked hyper-IgM syndrome". Orphanet. Retrieved...
healthy child initiates the production of host immunoglobulin G (IgG), immunoglobulinM (IgM), and immunoglobulin A (IgA) antibodies; IgG antibodies persist...
serologic tests measure one of two types of antibodies: immunoglobulinM (IgM) and immunoglobulin G (IgG). IgM is produced in high quantities shortly after a person...
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