Abnormal fatigue of unknown origin that persists for at least 6 months
This article is about chronic fatigue that does not result from chronic fatigue syndrome or another illness. Not to be confused with medically explained Chronic Fatigue, Chronic fatigue syndrome, or Neurasthenia.
Family medicine, Internal medicine, Musculoskeletal
Symptoms
Chronic fatigue
Usual onset
Acquired (not lifelong)[1]
Duration
At least six consecutive months
Causes
Unknown
Diagnostic method
Based on symptoms. Diagnosis of exclusion requiring laboratory evaluation, physical and biopsychosocial assessment.[1]
Differential diagnosis
Occupational burnout; chronic fatigue due to a known medical condition such as chronic fatigue syndrome, overtraining
Treatment
Symptomatic
Frequency
6.2 to 64.2 per 1000[2]
Idiopathic chronic fatigue (ICF) or chronic idiopathic fatigue or insufficient/idiopathic fatigue[3] is a term used for cases of unexplained fatigue that have lasted at least six consecutive months[1] and which do not meet the criteria for Myalgic Encephalomyelitis/chronic fatigue syndrome.[4] Such fatigue is widely understood to have a profound effect on the lives of patients who experience it.[1][5]
^ abcdSaultz, J (2002-09-23). "Care of the Patient with Fatigue". In Taylor, Robert (ed.). Family Medicine: Principles and Practice. Springer Science & Business Media. pp. 465–469. ISBN 978-0-387-95400-4.
^Kim, Tae-Hun; Kim, Do-Hoon; Kang, Jung Won (2020-04-01). "Medicinal herbs for managing fatigue symptoms in patients with idiopathic chronic fatigue: A PRISMA compliant updated systematic review and meta-analysis of randomized controlled trials based on the GRADE approach". European Journal of Integrative Medicine. 35: 101069. doi:10.1016/j.eujim.2020.101069. ISSN 1876-3820. S2CID 214256657.
^Vincent, Ann; Brimmer, Dana J.; Whipple, Mary O.; Jones, James F.; Boneva, Roumiana; Lahr, Brian D.; Maloney, Elizabeth; St. Sauver, Jennifer L.; Reeves, William C. (December 2012). "Prevalence, Incidence, and Classification of Chronic Fatigue Syndrome in Olmsted County, Minnesota, as Estimated Using the Rochester Epidemiology Project". Mayo Clinic Proceedings. 87 (12): 1145–1152. doi:10.1016/j.mayocp.2012.08.015. ISSN 0025-6196. PMC 3518652. PMID 23140977.
^van Campen, C. (Linda) M. C.; Visser, Frans C. (June 19, 2021). "Comparing Idiopathic Chronic Fatigue and Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) in Males: Response to Two-Day Cardiopulmonary Exercise Testing Protocol". Healthcare. 9 (6): 683. doi:10.3390/healthcare9060683. PMC 8230194. PMID 34198946.
^Son, Chang-Gue (2019-06-01). "Differential diagnosis between "chronic fatigue" and "chronic fatigue syndrome"". Integrative Medicine Research. 8 (2): 89–91. doi:10.1016/j.imr.2019.04.005. ISSN 2213-4220. PMC 6522773. PMID 31193269.
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