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Hemocyanin information


Hemocyanin, copper containing domain
Single oxygenated functional unit from the hemocyanin of an octopus
Identifiers
SymbolHemocyanin_M
PfamPF00372
InterProIPR000896
PROSITEPDOC00184
SCOP21lla / SCOPe / SUPFAM
Available protein structures:
Pfam  structures / ECOD  
PDBRCSB PDB; PDBe; PDBj
PDBsumstructure summary
PDB1oxy :110-373 1nol :110-373 1lla :110-373

1ll1 :110-373 1hc1A:136-393 1hcyD:136-393 1hc6B:136-393 1hc4C:136-393 1hc3C:136-393

1hc5C:136-393 1hc2C:136-393
Hemocyanin, all-alpha domain
Crystal structure of hexameric haemocyanin from Panulirus interruptus refined at 3.2 angstroms resolution
Identifiers
SymbolHemocyanin_N
PfamPF03722
InterProIPR005204
PROSITEPDOC00184
SCOP21lla / SCOPe / SUPFAM
Available protein structures:
Pfam  structures / ECOD  
PDBRCSB PDB; PDBe; PDBj
PDBsumstructure summary
Hemocyanin, ig-like domain
crystallographic analysis of oxygenated and deoxygenated states of arthropod hemocyanin shows unusual differences
Identifiers
SymbolHemocyanin_C
PfamPF03723
InterProIPR005203
PROSITEPDOC00184
SCOP21lla / SCOPe / SUPFAM
Available protein structures:
Pfam  structures / ECOD  
PDBRCSB PDB; PDBe; PDBj
PDBsumstructure summary

Hemocyanins (also spelled haemocyanins and abbreviated Hc) are proteins that transport oxygen throughout the bodies of some invertebrate animals. These metalloproteins contain two copper atoms that reversibly bind a single oxygen molecule (O2). They are second only to hemoglobin in frequency of use as an oxygen transport molecule. Unlike the hemoglobin in red blood cells found in vertebrates, hemocyanins are not confined in blood cells, but are instead suspended directly in the hemolymph. Oxygenation causes a color change between the colorless Cu(I) deoxygenated form and the blue Cu(II) oxygenated form.[1]

  1. ^ Coates CJ, Nairn J (July 2014). "Diverse immune functions of hemocyanins". Developmental and Comparative Immunology. 45 (1): 43–55. doi:10.1016/j.dci.2014.01.021. PMID 24486681.

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Hemocyanin

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Hemocyanins (also spelled haemocyanins and abbreviated Hc) are proteins that transport oxygen throughout the bodies of some invertebrate animals. These...

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Respiratory pigment

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There are four major classifications of respiratory pigment: hemoglobin, hemocyanin, erythrocruorin–chlorocruorin, and hemerythrin. The heme-containing globin...

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Keyhole limpet hemocyanin

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Keyhole limpet hemocyanin (KLH) is a large, multisubunit, oxygen-carrying, metalloprotein that is found in the hemolymph of the giant keyhole limpet, Megathura...

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Hemolymph

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were long thought unnecessary in insects, but ancestral and functional hemocyanin has been found in the hemolymph. Insect "blood" generally does not carry...

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Blue Blood

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blue blood may refer to: Hemolymph, circulatory fluid colored blue by hemocyanin, a respiratory protein evident in most molluscs and some arthropods Nobility...

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Common octopus

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drop to 3% of its total oxygen uptake. The octopus' respiratory pigment, hemocyanin, also assists in increasing oxygen uptake. Octopuses can maintain a constant...

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Megathura crenulata

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hemoglobin, the hemocyanin is not bound to cells but is simply dissolved in the hemolymph, the fluid part of the blood. Keyhole limpet hemocyanin from Megathura...

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Red king crab

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leukocytes and the second-most common respiratory pigment called hemocyanin.: 488  Arthropod hemocyanin is a distinct variation specific to arthropods and is a...

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Gastropoda

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have a pallial lung. The respiratory protein in almost all gastropods is hemocyanin, but one freshwater pulmonate family, the Planorbidae, have hemoglobin...

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Green blood

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to: Green Blood (manga), a Japanese manga series by Masasumi Kakizaki Hemocyanin, a copper-based system of transporting oxygen in blood found in many molluscs...

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HC

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continua Hyperelastosis cutis or hereditary equine regional dermal asthenia Hemocyanin, a metalloprotein abbreviated Hc HC smoke, a US military designation for...

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Mollusca

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skeleton. The blood of these molluscs contains the respiratory pigment hemocyanin as an oxygen-carrier. The heart consists of one or more pairs of atria...

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Spider anatomy

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internal organs. The haemolymph contains hemocyanin, a respiratory protein similar in function to hemoglobin. Hemocyanin contains two copper atoms, tinting...

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Tectipleura

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Gutenberg-University Reports Findings in Blood Proteins (The evolution of hemocyanin genes in Tectipleura: a multitude of conserved introns in highly diverse...

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Aquatic insect

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water using a plastron or blood gill Storage of oxygen in hemoglobin and hemocyanin molecules in hemolymph Taking oxygen from surface via breathing tubes...

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Book lung

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appears to be the only members of Arachnida where the respiratory pigment hemocyanin is present in their blood. One of the long-running controversies in arachnid...

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Solifugae

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tracheae, with tracheoles penetrating the epithelia of internal organs. Hemocyanin, a respiratory pigment common in the hemolymph of many arachnids and other...

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Circulatory system

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carbohydrates, proteins, and lipids). The primary oxygen transporter molecule is hemocyanin. There are free-floating cells, the hemocytes, within the hemolymph. They...

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Arthropod

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transport. The most common respiratory pigment in arthropods is copper-based hemocyanin; this is used by many crustaceans and a few centipedes. A few crustaceans...

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Copper

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molluscs and crustaceans, copper is a constituent of the blood pigment hemocyanin, replaced by the iron-complexed hemoglobin in fish and other vertebrates...

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Spider

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of many spiders that have book lungs contains the respiratory pigment hemocyanin to make oxygen transport more efficient. Spiders have developed several...

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Cephalopod

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environments with little oxygen and in low temperatures, hemocyanin has the upper hand. The hemocyanin molecule is much larger than the hemoglobin molecule...

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Hemerythrin

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contain a heme. The names of the blood oxygen transporters hemoglobin, hemocyanin, and hemerythrin do not refer to the heme group (only found in globins)...

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Branchial heart

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anaerobic conditions. Branchial hearts also appear to be involved in hemocyanin synthesis. Each branchial heart is directly connected to a branchial heart...

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Immunogen

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the terms immunogen and antigen were not distinguished. Keyhole limpet hemocyanin It is copper-containing respiratory protein, isolated from keyhole limpets...

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Vanabin

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used for oxygen transport like iron-based hemoglobin or copper-based hemocyanin. Unfortunately no scientific evidence can be found to back this hypothesis...

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Giant Pacific octopus

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available habitat/den space) Because their blue blood is copper-based (hemocyanin) and not an efficient oxygen carrier, octopuses favor and move toward...

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Lobster

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Lobsters, like snails and spiders, have blue blood due to the presence of hemocyanin, which contains copper. In contrast, vertebrates, and many other animals...

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Hemoglobin

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cooperative binding. It is used to store oxygen rather than transport it. Hemocyanin The second most common oxygen-transporting protein found in nature, it...

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Transition metal dioxygen complex

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oxygen-carrying proteins such as myoglobin, hemoglobin, hemerythrin, and hemocyanin. Several transition metals form complexes with O2, and many of these complexes...

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