chondrocyte development involved in endochondral bone morphogenesis
collagen biosynthetic process
collagen fibril organization
negative regulation of endopeptidase activity
Sources:Amigo / QuickGO
Orthologs
Species
Human
Mouse
Entrez
871
12406
Ensembl
ENSG00000149257
ENSMUSG00000070436
UniProt
P50454
P19324
RefSeq (mRNA)
NM_001207014 NM_001235
NM_001111043 NM_001111044 NM_009825 NM_001285776
RefSeq (protein)
NP_001193943 NP_001226
NP_001104513 NP_001104514 NP_001272705 NP_033955
Location (UCSC)
Chr 11: 75.56 – 75.57 Mb
Chr 7: 98.99 – 99 Mb
PubMed search
[3]
[4]
Wikidata
View/Edit Human
View/Edit Mouse
Heat shock protein 47, also known as SERPINH1 is a serpin which serves as a human chaperone protein for collagen.[5][6]
^ abcGRCh38: Ensembl release 89: ENSG00000149257 – Ensembl, May 2017
^ abcGRCm38: Ensembl release 89: ENSMUSG00000070436 – Ensembl, May 2017
^"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Entrez Gene: SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)".
^Dafforn TR, Della M, Miller AD (December 2001). "The molecular interactions of heat shock protein 47 (Hsp47) and their implications for collagen biosynthesis". The Journal of Biological Chemistry. 276 (52): 49310–9. doi:10.1074/jbc.M108896200. PMID 11592970.
and 28 Related for: Heat shock protein 47 information
Heatshockprotein47, also known as SERPINH1 is a serpin which serves as a human chaperone protein for collagen. This protein is a member of the serpin...
The 70 kilodalton heatshockproteins (Hsp70s or DnaK) are a family of conserved ubiquitously expressed heatshockproteins. Proteins with similar structure...
Hsp90 (heatshockprotein 90) is a chaperone protein that assists other proteins to fold properly, stabilizes proteins against heat stress, and aids in...
The heatshockprotein Hsp20 family, also known as small heatshockproteins (sHSPs), is a family of heatshockproteins. Prokaryotic and eukaryotic organisms...
cellular respiration, protein catabolism, and metabolic acidosis with a compensatory respiratory alkalosis. Most cases of septic shock are caused by gram-positive...
"Exogenous nitric oxide enhances the synthesis of type I collagen and heatshockprotein47 by normal human dermal fibroblasts". Journal of Dermatological Science...
an intron-less gene which encodes for the heatshockprotein HSP70-2, a member of the Hsp70 family of proteins. The gene is located in the major histocompatibility...
temperatures, heat-shockproteins, including chaperones and proteases are rapidly induced to protect against the denaturation of proteins within the bacteria...
cytosolic proteins, will trimerize and enter the nucleus to upregulate the expression of heatshockproteins (HSPs) that will act as protein folding chaperones...
abundant protein in egg white. Its exact function is unknown, but it is thought to be a storage protein for the developing foetus. Heatshock serpin 47 is a...
methods, solutions of heat equations have been useful in the mathematical formulation of hydrodynamical shocks. Solutions of the heat equation have also...
Saharan silver ants produce heatshockproteins (HSPs), but unlike other animals, they do this not in direct response to heat. Instead, they do this before...
Heatshock 10 kDa protein 1 (Hsp10), also known as chaperonin 10 (cpn10) or early-pregnancy factor (EPF), is a protein that in humans is encoded by the...
regular yield damages between 10 and 15%. Many plant hosts produce heatshockprotein 70s including C. arietinum. In response to F. o. ciceris Gupta et...
a co-inducer of heatshockproteins, on sensory fibers of the rat following peripheral nerve injury". Exp. Neurol. 184 (2): 636–47. doi:10.1016/S0014-4886(03)00343-1...
stresses – such as infection, heatshock, or oxidative damage – heatshockproteins that identify misfolded or unfolded proteins and target them for proteasomal...
competent cells, the length of time of heatshock, temperature of heatshock, incubation time after heatshock, growth medium used, pH and various additives...
microsomal protein factions. Heatshock affected the abundance of HSPs depending on protein fraction and time of day. Without heatshock, nuclear membrane-bound...
subunits (A and B) that are highly similar to the small (15-30kDa) heatshockproteins (sHsps), particularly in their C-terminal halves. The relationship...
ubiquitin ligase) is a protein that recruits an E2 ubiquitin-conjugating enzyme that has been loaded with ubiquitin, recognizes a protein substrate, and assists...
Medical Center, and University of California San Francisco, offering heatshockprotein vaccine clinical trials in neurooncology treatment. These clinical...
(September 1988). "Association of the dioxin receptor with the Mr 90,000 heatshockprotein: a structural kinship with the glucocorticoid receptor". Biochemical...
kDa heatshockprotein ATPase homolog 1 is an enzyme that in humans is encoded by the AHSA1 gene. AHSA1 has been shown to interact with Heatshock protein...
allowed to refold either by itself or with the help of heatshockproteins. Misfolded proteins can be eliminated through the ubiquitin-proteasome system...
expression. KLF13 has been shown to interact with CREB-binding protein, Heatshockprotein47 and PCAF. Kruppel-like factors ENSG00000275746 GRCh38: Ensembl...
membrane attack complex. About 50 proteins and protein fragments make up the complement system, including plasma proteins, and cell membrane receptors. They...
precursor proteins Chaperone involvement in the IMS has been proposed but still remains uncertain. The eukaryotic Hsp70, which is the heatshockprotein of 70...