HOXB2 information

HOXB2
Identifiers
Aliases	HOXB2, HOX2, HOX2H, Hox-2.8, K8, homeobox B2
External IDs	OMIM: 142967; MGI: 96183; HomoloGene: 37584; GeneCards: HOXB2; OMA:HOXB2 - orthologs
Gene location (Human)
Chr.	Chromosome 17 (human)
End	48,545,109 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	96,244,838 bp
RNA expression pattern
	Top expressed in
	seminal vesicula; ; right uterine tube; ; corpus epididymis; ; muscle layer of sigmoid colon; ; caput epididymis; ; left coronary artery; ; gastric mucosa; ; Descending thoracic aorta; ; right coronary artery; ; canal of the cervix;
	Top expressed in
	embryo; ; somite; ; tail of embryo; ; transitional epithelium of urinary bladder; ; seminal vesicula; ; proximal tubule; ; adrenal gland; ; right kidney; ; enteric nervous system; ; medullary collecting duct;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	DNA-binding transcription factor activity; DNA binding; DNA-binding transcription activator activity, RNA polymerase II-specific; sequence-specific DNA binding; DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding;
Cellular component	nucleus; nucleoplasm; cytosol; nuclear speck;
Biological process	multicellular organism development; regulation of transcription, DNA-templated; blood circulation; transcription, DNA-templated; morphogenesis of an epithelial sheet; anterior/posterior pattern specification; dorsal/ventral pattern formation; rhombomere 3 development; rhombomere 4 development; facial nerve structural organization; embryonic skeletal system morphogenesis; skeletal system morphogenesis; neural nucleus development; transcription by RNA polymerase II; positive regulation of transcription by RNA polymerase II;
	Sources:Amigo / QuickGO
Orthologs
	3212
	103889
	ENSG00000173917
	ENSMUSG00000075588
	P14652
	P0C1T1
	NM_002145
	NM_134032
	NP_002136
	NP_598793
	Wikidata
View/Edit Human	View/Edit Mouse

Homeobox protein Hox-B2 is a protein that in humans is encoded by the HOXB2 gene.^[5]^[6]^[7]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000173917 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000075588 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ McAlpine PJ, Shows TB (Jul 1990). "Nomenclature for human homeobox genes". Genomics. 7 (3): 460. doi:10.1016/0888-7543(90)90186-X. PMID 1973146.
^ Scott MP (Nov 1992). "Vertebrate homeobox gene nomenclature". Cell. 71 (4): 551–3. doi:10.1016/0092-8674(92)90588-4. PMID 1358459. S2CID 13370372.
^ "Entrez Gene: HOXB2 homeobox B2".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000173917 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000075588 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid1973146-5] McAlpine PJ, Shows TB (Jul 1990). "Nomenclature for human homeobox genes". Genomics. 7 (3): 460. doi:10.1016/0888-7543(90)90186-X. PMID 1973146.

[pmid1358459-6] Scott MP (Nov 1992). "Vertebrate homeobox gene nomenclature". Cell. 71 (4): 551–3. doi:10.1016/0092-8674(92)90588-4. PMID 1358459. S2CID 13370372.

[entrez-7] "Entrez Gene: HOXB2 homeobox B2".

HOXB2 information

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HOXB2

Hox gene

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List of human transcription factors

EGR2

MEIS1

PBX1

HOXB1

HOXB3

PKNOX1