Homeobox protein Hox-B3 is a protein that in humans is encoded by the HOXB3 gene.[5][6][7]
This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in development. Increased expression of this gene is associated with a distinct biologic subset of acute myeloid leukemia (AML).[7]
^ abcGRCh38: Ensembl release 89: ENSG00000120093 – Ensembl, May 2017
^ abcGRCm38: Ensembl release 89: ENSMUSG00000048763 – Ensembl, May 2017
^"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^McAlpine PJ, Shows TB (Aug 1990). "Nomenclature for human homeobox genes". Genomics. 7 (3): 460. doi:10.1016/0888-7543(90)90186-X. PMID 1973146.
Homeobox protein Hox-B3 is a protein that in humans is encoded by the HOXB3 gene. This gene is a member of the Antp homeobox family and encodes a nuclear...
components of the ECM. HoxA5 is implicated in atherosclerosis. HoxD3 and HoxB3 are proinvasive, angiogenic genes that upregulate b3 and a5 integrins and...
ENSG00000173917 Homeodomain Known motif – High-throughput in vitro [385] TAATKR HOXB3 ENSG00000120093 Homeodomain Known motif – High-throughput in vitro [386]...
kreisler co-operate in the transcriptional control of segmental expression of Hoxb3 in the developing hindbrain". The EMBO Journal. 21 (3): 365–76. doi:10.1093/emboj/21...
(May 1998). "Regulatory interactions between the human HOXB1, HOXB2, and HOXB3 proteins and the upstream sequence of the Otx2 gene in embryonal carcinoma...