Epstein's pearl shown in the roof of the mouth on a five-week-old infant
Specialty
Dentistry
Gingival cyst, also known as Epstein's pearl, is a type of cysts of the jaws that originates from the dental lamina and is found in the mouth parts. It is a superficial cyst in the alveolar mucosa. It can be seen inside the mouth as small and whitish bulge. Depending on the ages in which they develop, the cysts are classified into gingival cyst of newborn (or infant) and gingival cyst of adult.[1] Structurally, the cyst is lined by thin epithelium and shows a lumen usually filled with desquamated keratin, occasionally containing inflammatory cells. The nodes are formed as a result of cystic degeneration of epithelial rests of the dental lamina (called the rests of Serres).[2]
Gingival cyst was first described by a Czech physician Alois Epstein in 1880.[3] In 1886, a German physician Heinrich Bohn described another type of cyst. Alfred Fromm introduced the classification of gingival cysts in 1967.[4] According to him, gingival cysts of newborns can be further classified based on their specific origin of the tissues as Epstein’s pearls, Bohn’s nodules and dental lamina cysts.[5]
^Browne, Roger M. (1991). "The Classification of Odontogenic Cysts". In Browne, Roger M. (ed.). Investigative Pathology of Odontogenic Cysts. Boca Raton, Florida: CRC Press. pp. 7–9. ISBN 978-0-8493-5038-2.
^Moda, Aman; Das, Usha Mohan (2011). "Gingival Cyst of Newborn". International Journal of Clinical Pediatric Dentistry. 4 (1): 83–84. doi:10.5005/jp-journals-10005-1087. PMC 4999644. PMID 27616865.
^Singh, RK; Kumar, R; Pandey, RK; Singh, K (2012). "Dental lamina cysts in a newborn infant". BMJ Case Reports. 2012 (bcr2012007061): bcr2012007061. doi:10.1136/bcr-2012-007061. PMC 4544414. PMID 23048002.
^Fromm, A. (1967). "Epstein's pearls, Bohn's nodules and inclusion-cysts of the oral cavity". Journal of Dentistry for Children. 34 (4): 275–287. PMID 5342399.
^Lewis, D.M. (2010). "Bohn's nodules, Epstein's pearls, and gingival cysts of the newborn: a new etiology and classification". Journal - Oklahoma Dental Association. 101 (3): 32–33. PMID 20397339.
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