A De Finetti diagram visualizing genotype frequencies as distances to triangle edges x (AA), y (Aa) and z (aa) in a ternary plot. The curved line are the Hardy–Weinberg equilibria.A Punnett square visualizing the genotype frequencies of a Hardy–Weinberg equilibrium as areas of a square. p (A) and q (a) are the allele frequencies.
Genetic variation in populations can be analyzed and quantified by the frequency of alleles. Two fundamental calculations are central to population genetics: allele frequencies and genotype frequencies.[1]Genotype frequency in a population is the number of individuals with a given genotype divided by the total number of individuals in the population.[2]
In population genetics, the genotype frequency is the frequency or proportion (i.e., 0 < f < 1) of genotypes in a population.
Although allele and genotype frequencies are related, it is important to clearly distinguish them.
Genotype frequency may also be used in the future (for "genomic profiling") to predict someone's having a disease[3] or even a birth defect.[4] It can also be used to determine ethnic diversity.
Genotype frequencies may be represented by a De Finetti diagram.
^Brooker R, Widmaier E, Graham L, and Stiling P. Biology (2011): p. 492
^Brooker R, Widmaier E, Graham L, and Stiling P. Biology (2011): p. G-14
^Janssens; et al. "Genomic profiling: the critical importance of genotype frequency". PHG Foundation.
^Shields; et al. (1999). "Neural Tube Defects: an Evaluation of Genetic Risk". American Journal of Human Genetics. 64 (4): 1045–1055. doi:10.1086/302310. PMC 1377828. PMID 10090889.
and 24 Related for: Genotype frequency information
the frequency of alleles. Two fundamental calculations are central to population genetics: allele frequencies and genotypefrequencies. Genotype frequency...
allele frequency is distinct from the genotypefrequency, although they are related, and allele frequencies can be calculated from genotypefrequencies. In...
"A" alleles.) The frequency of alleles in a diploid population can be used to predict the frequencies of the corresponding genotypes (see Hardy–Weinberg...
fertilization occurred continually, it would maintain the same allele and genotypefrequencies across each successive panmictic sexual generation—this being the...
been empirically verified. European population estimates for A1+ genotypefrequencies range from 20.8 to 43.4% (National Center of Biotechnology Information...
double heterozygotes with genotype AaBb. The F1 offspring AaBb produces gametes that are AB, Ab, aB, and ab with equal frequencies (25%) because the alleles...
population is in an internal Hardy–Weinberg equilibrium, so that the genotypefrequencies AA, Aa and aa are p2, 2pq, and q2 respectively for each population...
SNP genotyping is the measurement of genetic variations of single nucleotide polymorphisms (SNPs) between members of a species. It is a form of genotyping...
S2CID 31026948. Eng MY, Luczak SE, Wall TL (2007). "ALDH2, ADH1B, and ADH1C genotypes in Asians: a literature review". Alcohol Research & Health. 30 (1): 22–27...
allele frequencies. This nonrandom mating pattern will result in deviation from the Hardy-Weinberg principle (which states that genotypefrequencies in a...
loci. Each genotype (combination of alleles) is represented by a circle which has an area proportional to the frequency of that genotype, with a column...
to test whether single-locus alleles or genotypefrequencies or more generally, multilocus haplotype frequencies differ between two groups of individuals...
combining the data from multiple submissions (e.g. heterozygosity, genotypefrequencies). Many tools are available to examine a refSNP cluster in greater...
change in genotypefrequencies attributable to selection. The following definition of s is commonly used. Suppose that there are two genotypes A and B in...
the 1000 Genomes Project and has since been used by other large-scale genotyping and DNA sequencing projects. VCF is a common output format for variant...
sexual diploids, idealized populations will have genotypefrequencies related to the allele frequencies according to Hardy-Weinberg equilibrium. In 1908...
publications of his first paper on the "thrifty genotype" hypothesis, Neel researched the frequency of diabetes and (increasingly) obesity in a number...
trend. The same principle may be applied to the effects of allele/genotypefrequency, where it could be argued that SNPs in nucleotides XX, XY, YY are...
allele, expressed as a fraction or percentage. Allele frequency is distinct from genotypefrequency, although they are related. allochronic isolation The...
statistician Bruno de Finetti (1906–1985) and is used to graph the genotypefrequencies of populations, where there are two alleles and the population is...
hosts in order to reduce the risk of infection. Oscillations in genotypefrequencies are observed between parasites and hosts in an antagonistic coevolutionary...
inheritance of the GG or GA genotype is observed while the AA genotype is recessive. The phenotypes expressed by the genotypes include cerumen type (wet...
composed of three species. In population genetics, a triangle plot of genotypefrequencies is called a de Finetti diagram. In game theory, it is often called...
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