Genetically modified sperm (GM sperm) is sperm that has undergone genetic modification for biomedical purposes, including the elimination of genetic diseases or infertility.[1] Although the procedure has been tested on animals such as fish,[2] pigs,[3] and rabbits,[4] it remains relatively untested on humans.[5] In the case of pigs, the goal of research is to inexpensively produce organs and supplement the shortage of donated human organs.[6] Although GM sperm has the potential to detect and treat genetic diseases, it will likely take many years for successful use in patients.
^"Animals From Genetically Modified Sperm". Archived from the original on 2012-07-23. Retrieved 2009-11-26.
^Genetically modified sperm in fish
^Manzini, S.; Vargiolu, A.; Stehle, I.; Bacci, M.; Cerrito, M.; Giovannoni, R.; Zannoni, A.; Bianco, M.; Forni, M.; Donini, P.; Papa, M.; Lipps, H. J.; Lavitrano, M. (2006). "Genetically modified pigs produced with a nonviral episomal vector". Proceedings of the National Academy of Sciences of the United States of America. 103 (47): 17672–17677. Bibcode:2006PNAS..10317672M. doi:10.1073/pnas.0604938103. PMC 1635978. PMID 17101993.
^Wang, H. J.; Lin, A. X.; Zhang, Z. C.; Chen, Y. F. (2001). "Expression of porcine growth hormone gene in transgenic rabbits as reported by green fluorescent protein". Animal Biotechnology. 12 (2): 101–110. doi:10.1081/ABIO-100108336. PMID 11808625. S2CID 23132238.
^Scientists 'five years away' from creating human sperm and eggs in a laboratory
^"Human genes placed in pigs". The Cincinnati Post. 2002-10-22. Archived from the original on 2012-11-03. Retrieved 2010-02-08.
and 27 Related for: Genetically modified sperm information
Geneticallymodifiedsperm (GM sperm) is sperm that has undergone genetic modification for biomedical purposes, including the elimination of genetic diseases...
Geneticallymodified animals are animals that have been geneticallymodified for a variety of purposes including producing drugs, enhancing yields, increasing...
A geneticallymodified organism (GMO) is any organism whose genetic material has been altered using genetic engineering techniques. The exact definition...
Geneticallymodified fish (GM fish) are organisms from the taxonomic clade which includes the classes Agnatha (jawless fish), Chondrichthyes (cartilaginous...
extant species in the sperm whale family, along with the pygmy sperm whale and dwarf sperm whale of the genus Kogia. The sperm whale is a pelagic mammal...
criticism. Genetically altered embryos can be achieved by introducing the desired genetic material into the embryo itself, or into the sperm and/or egg...
established the need of interaction between the female's ovum and male's sperm to form a zygote in frogs. In 1827, Karl Ernst von Baer observed a therian...
Sperm competition is the competitive process between spermatozoa of two or more different males to fertilize the same egg during sexual reproduction....
Projects Agency (DARPA) describing a tender for contracts to develop geneticallymodified plant viruses for an approach involving their dispersion into the...
that every fetus has a right to remain genetically unmodified, that parents hold the right to geneticallymodify their offspring, and that every child...
followed before a geneticallymodified organism (GMO) is created. Genetic engineers must first choose what gene they wish to insert, modify, or delete. The...
produces offspring by the fusion of gametes, resulting in offspring genetically different from either parent. Asexual reproduction produces new individuals...
transformed into spermatozoa (sperm) by the process of spermiogenesis. These develop into mature spermatozoa, also known as sperm cells. Thus, the primary...
Genetic incompatibility describes the process by which mating yields offspring that are nonviable, prone to disease, or genetically defective in some...
naturally prevent malaria. Serratia a genus of bacteria that can be geneticallymodified to prevent malaria. "Genome Sequence of the Intracellular Bacterium...
(egg cell), the type of gamete (sex cell) that fuses with the male gamete (sperm cell) during sexual reproduction. A female has larger gametes than a male...
DNA to create a geneticallymodified, transgenic animal. The creation of transgenic animals also leads into the study of altering sperm cells with exogenous...
Identical siblings are genetically the same since they come from the same zygote. Meanwhile, fraternal twins are as genetically different from one another...
typically not as genetically diverse or extensive. These collections are susceptible to hybridization, artificial selection, genetic drift, and disease...
sperm over the unfertilized eggs. Other species of fish are oviparous and have internal fertilization aided by pelvic or anal fins that are modified into...
(Kogia breviceps) and dwarf (K. sima) sperm whales. As their common names suggest, they somewhat resemble sperm whales, with squared heads and small lower...
"animalcules" in the sperm of humans and other animals. Some scientists speculated they saw a "little man" (homunculus) inside each sperm. These scientists...
involves procedures such as in vitro fertilization (IVF), intracytoplasmic sperm injection (ICSI), cryopreservation of gametes or embryos, and/or the use...
helps transport sperm to the genital ducts. The ductuli efferentes possess cuboidal cells with microvilli and lysosomal granules that modify the ductal fluid...
parthenogenesis can mean the development of an embryo from either an individual sperm or an individual egg. Parthenogenesis occurs naturally in some plants, algae...
geneticallymodified babies and such experiments would have ethical issues as the safety and success were not yet warranted by any study, and genetic...
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