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GeneMark is a generic name for a family of ab initio gene prediction algorithms and software programs developed at the Georgia Institute of Technology in Atlanta. Developed in 1993, original GeneMark was used in 1995 as a primary gene prediction tool for annotation of the first completely sequenced bacterial genome of Haemophilus influenzae, and in 1996 for the first archaeal genome of Methanococcus jannaschii. The algorithm introduced inhomogeneous three-periodic Markov chain models of protein-coding DNA sequence that became standard in gene prediction as well as Bayesian approach to gene prediction in two DNA strands simultaneously. Species specific parameters of the models were estimated from training sets of sequences of known type (protein-coding and non-coding). The major step of the algorithm computes for a given DNA fragment posterior probabilities of either being "protein-coding" (carrying genetic code) in each of six possible reading frames (including three frames in the complementary DNA strand) or being "non-coding". The original GeneMark (developed before the advent of the HMM applications in Bioinformatics) was an HMM-like algorithm; it could be viewed as approximation to known in the HMM theory posterior decoding algorithm for appropriately defined HMM model of DNA sequence.
GeneMark is a generic name for a family of ab initio gene prediction algorithms and software programs developed at the Georgia Institute of Technology...
America with Gene and John". Audioboom. "GeneMarks: Keynote Speaker on Economic, Technology, Political, and Management Trends". genemarks.com. Marks, G. (2022...
widely used and highly accurate gene finder for prokaryotes. GeneMark is another popular approach. Eukaryotic ab initio gene finders, by comparison, have...
PMID 9149143. Archived from the original (PDF) on 2015-06-20. "GeneMark-ES". Lomsadze A (2005). "Gene finding in novel genomes by self-training algorithm". Nucleic...
made many contributions in the area of development of gene finding algorithms, notably the GeneMark program (1993) that made an impact in the field and...
types of molecular genes: protein-coding genes and non-coding genes. During gene expression (the synthesis of RNA or protein from a gene), DNA is first copied...
identifies the genes encoding all proteins, transfer RNAs, ribosomal RNAs, in order to make initial functional assignments. The GeneMark program trained...
Gene Rayburn (born Eugene Peter Jeljenic; December 22, 1917 – November 29, 1999) was an American radio and television personality. He is best known as...
Hox genes, a subset of homeobox genes, are a group of related genes that specify regions of the body plan of an embryo along the head-tail axis of animals...
coding regions based upon gene training sets from related organisms. This is the approach taken by programs such as GeneMark and GLIMMER. The main advantage...
"Gene Principe Bio - Sportsnet.ca". Sportsnet.ca. January 17, 2014. Archived from the original on January 17, 2014. Retrieved December 18, 2021. "Gene...
Gene Wilder (né Jerome Silberman, June 11, 1933 – August 29, 2016) was an American actor, comedian, writer and filmmaker. He was mainly known for his comedic...
Orvon Grover "Gene" Autry (September 29, 1907 – October 2, 1998), nicknamed the Singing Cowboy, was an American actor, musician, singer, composer, rodeo...
finale of The Eric Andre Show on Adult Swim. Gene endorses and uses Pearl Drums, Sabian cymbals, Pro-Mark sticks and Evans heads. Drums – Pearl Reference...
every phage in the database. Along with all these, there is a separate GeneMark page for each phage which allows one to cross reference the position of...
Gene expression is the process by which information from a gene is used in the synthesis of a functional gene product that enables it to produce end products...
Warith Deen Umar (born Wallace GeneMarks, 1945) is a New York-area imam and resident of Bethlehem, New York. He was formerly the head Muslim chaplain...
The Selfish Gene is a 1976 book on evolution by ethologist Richard Dawkins, in which the author builds upon the principal theory of George C. Williams's...
Gary Gene Watson (born October 11, 1943) is an American country music singer. He is most famous for his 1975 hit "Love in the Hot Afternoon," his 1981...
Eugene Biography, Songs, & Albums". AllMusic. "Gene Eugene Albums and Discography". AllMusic. Powell, Mark Allan (2002). Encyclopedia of Contemporary Christian...
Minneapolis where he worked for WDGY as a radio host under the alias of Gene Leader. He later left that position to become Program Director at KDWB. Okerlund...
Gene silencing is the regulation of gene expression in a cell to prevent the expression of a certain gene. Gene silencing can occur during either transcription...
Mark Christopher Lawrence (born May 22, 1964) is an American character actor, stand-up comedian and voice-over artist. He is known for his role as esoteric...
Gene Simmons (born Chaim Witz; Hebrew: חיים ויץ [χaˈim ˈvits]; born August 25, 1949) is an Israeli-American musician. Also known by his stage persona "The...
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