Gene amplification information

Gene amplification refers to a number of natural and artificial processes by which the number of copies of a gene is increased "without a proportional...

Gene duplication (or chromosomal duplication or gene amplification) is a major mechanism through which new genetic material is generated during molecular...

Turlotte E (November 1998). "[A method of isothermal gene amplification]" [An Isothermal Amplification Method]. Comptes Rendus de l'Académie des Sciences...

colon, and most notably, neuroblastoma. They are a manifestation of gene amplification as a result of chromothripsis, during the development of tumors, which...

Gene amplification in Paramecium tetraurelia is an example of gene amplification that has occurred in the unicellular organism Paramecium tetraurelia....

then be amplified with additional copies of the gene. Such a rapid amplification is best known from bacteria that often carry certain genes on smaller...

chromosomal aneuploidy and gene amplification as the reference gene will also be amplified in aneuploidy but not in gene amplification detection. Tanner, M;...

alterations (e.g. gene amplification and deletion) and epigenetic modifications. Cancer cells are constantly using a variety of tools, involving genes, proteins...

driver oncogenes. ecDNA is considered to be a primary mechanism of gene amplification, resulting in many copies of driver oncogenes and very aggressive...

product of an amplification reaction, amplicon is used interchangeably with common laboratory terms, such as "PCR product." Artificial amplification is used...

introducing them to mutagens. Another way to increase production is by gene amplification, this is done by the use of plasmids, and vectors. The plasmids and/...

stressor acts on a species. Gene amplification is more common in bacteria and is a reversible process. Contraction of gene families commonly results from...

in early steps of amplification will "swamp out" any specific sequences because of the exponential nature of polymerase amplification. The earliest steps...

~10% of colorectal carcinomas, cyclin E gene amplification is found, sometimes together with CDK2 gene amplification. Cyclin E is also a useful prognostic...

nonexpressed genes. Some of the expressed genes differ in their transcriptional regulation. Gene amplification appears to be in blocks of genes explaining...

limitless cell proliferation to occur. Gene amplification often occur in various tumor cases, including of MDM2, a gene encodes for a RING E3 Ubiquitin ligase...

and control amplification, it is crucial to take into consideration the starting target molecules concentration and their amplification rate prior to...

copies of the AR gene (amplification) have been observed in anti-androgen resistant prostate cancer. These additional copies of the gene are thought to...

uncontrolled cell growth from occurring. Amplification, also known as the over-expression of the ERBB2 gene, occurs in approximately 15-30% of breast...

the phenomenon was due to general hypermutability due to selected gene amplification, followed by natural selection, and was thus a standard Darwinian...

Miz-1 target genes. In addition, myc has a direct role in the control of DNA replication. This activity could contribute to DNA amplification in cancer cells...

tumors, and more specifically the amplification of oncogenes and drug-resistant genes. This also supports that the genes on eccDNA are expressed. Overall...

Nagtegaal ID, Paraf F, Lauricella C, et al. (September 2013). "KRAS gene amplification in colorectal cancer and impact on response to EGFR-targeted therapy"...

awarded a PhD from Imperial College London for research investigating gene amplification in rat cells in 1990 while working at the Imperial Cancer Research...

or more. Another technique used to increase yields is gene amplification, where copies of genes coding for enzymes involved in the antibiotic production...