Protein produced by artificial modification of vitamin D-binding protein
GcMAF (or Gc protein-derived macrophage activating factor) is a protein produced by modification of vitamin D-binding protein.[1] It has been falsely promoted as a treatment for various medical conditions, but claims of its benefits are not supported by evidence.
Once proclaimed a 'magic protein' capable of curing cancer, GcMAF has been proven ineffective. The case sheds light on how far scammers are willing to go to exploit desperate cancer patients and their families for financial gain.
Public warning issued by the Anticancer Fund[2]
Biochemically, GcMAF results from sequential deglycosylation of the vitamin D-binding protein (the Gc protein), which is naturally promoted by lymphocytes (B and T cells).[3] The resulting protein may be a macrophage activating factor (MAF).[3] MAFs are lymphokines that control the expression of antigens on the surface of macrophages, and one of their functions is to make macrophages become cytotoxic to tumors.[4]
^Galactosidases — Advances in Research and Application. Scholarly Editions. 21 June 2013. p. 52. ISBN 978-1-4816-8801-7.
^Cite error: The named reference Anticancer Fund was invoked but never defined (see the help page).
^ abMalik, Suneil; Fu, Lei; Juras, David James; Karmali, Mohamed; Wong, Betty Y. L.; Gozdzik, Agnes; Cole, David E. C. (January–February 2013). "Common variants of the vitamin D binding protein gene and adverse health outcomes". Critical Reviews in Clinical Laboratory Sciences. 50 (1): 1–22. doi:10.3109/10408363.2012.750262. PMC 3613945. PMID 23427793.
^Mosser, David M. (February 2003). "The many faces of macrophage activation". Journal of Leukocyte Biology. 73 (2): 209–212. doi:10.1189/jlb.0602325. PMID 12554797.
GcMAF (or Gc protein-derived macrophage activating factor) is a protein produced by modification of vitamin D-binding protein. It has been falsely promoted...
politician, who founded Immuno Biotech Ltd. to promote the unproven therapy GcMAF and came last in the 2006 UKIP leadership election. He pleaded guilty to...
Bradstreet used on autistic children included the controversial protein GcMAF, with which he claimed to have treated 600 children. In an article for an...
life, he dedicated time and resources to the research and development of GcMAF therapy, an immune boosting injection that has been successful in treating...
Maf subfamily (c-Maf, MafA, MafB, and NRL); and the small Maf subfamily (MafF, MafG and MafK) (Fig. 1). The first member of the Maf family is c-Maf,...
job to FDA and confirms her own safety application as FDA manager. 5th GcMAF Conference - 2017 Moscow - Speaker: Scott Tipps - National Health Federation[unreliable...
Midland International Air and Space Port (IATA: MAF, ICAO: KMAF, FAA LID: MAF) (formerly Midland International Airport) is in the city limits of Midland...
Fragment antigen-binding Fragment crystallizable region Freund's adjuvant Gc-MAF Gluten immunochemistry Glycoprotein 130 Graft versus tumor effect Granulocyte...
U.S. Food and Drug Administration as a prime example of a "rip-off". Gc-MAF (Gc protein-derived macrophage activating factor) – a type of protein that...
Norihiro (1 August 2014). "Case Report: A Breast Cancer Patient Treated with GcMAF, Sonodynamic Therapy and Hormone Therapy". Anticancer Research. 34 (8):...
concerning cancer and cancer treatments. An example of this is the drug GcMAF, which has been promoted as a miracle cure for several illnesses including...
Transcription factor MafK is a bZip Maf transcription factor protein that in humans is encoded by the MAFK gene. MafK is one of the small Maf proteins, which...
1001 2017 MAA 1001, MAB 1001, MAC 1001, MAD 1001 2018 MAD 5001, MAE 1001, MAF 1001, MAG 1001 2019 MAH 1001, MAI 1001, MAJ 1001, MAK 1001 Region XIII (Caraga)...
1935 OHV air-cooled single MAC (WD) 349 cc 1940 Military version of MAC MAF 349 cc 1941 Improved version of MAC (WD) Velocette LE 149 cc 1951 Telescopic...
Transcription factor MafG is a bZip Maf transcription factor protein that in humans is encoded by the MAFG gene. MafG is one of the small Maf proteins, which...
of a MAP sensor and Intake Air Temp Sensor, unlike the EJ253 which uses a MAF sensor. Compression ratio is 10:1. Power ISO: 123 kW (165 hp; 167 PS) at...
general-purpose compression utilities. For this, Chanda, Elhaik, and Bader introduced MAF-based encoding (MAFE), which reduces the heterogeneity of the dataset by...
response from developed countries. Technologies such as the ones used by MAF allows health professionals in remote clinics to have internet access, making...
(Feb 2009). "The costimulatory molecule ICOS regulates the expression of c-Maf and IL-21 in the development of follicular T helper cells and TH-17 cells"...
Global Information