dentate gyrus of hippocampal formation granule cell
ascending aorta
epithelium of lens
right kidney
atrioventricular valve
More reference expression data
BioGPS
n/a
Gene ontology
Molecular function
transmembrane transporter binding
protein binding
frizzled binding
protein C-terminus binding
GTPase regulator activity
protein homodimerization activity
Cellular component
lysosomal membrane
Golgi-associated vesicle membrane
trans-Golgi network transport vesicle
synapse
cell projection
cell junction
Golgi membrane
postsynaptic density
postsynaptic membrane
dendrite
membrane
Golgi apparatus
cytoplasm
plasma membrane
protein-containing complex
Biological process
endoplasmic reticulum to Golgi vesicle-mediated transport
protein homooligomerization
apical protein localization
protein transport
Golgi to plasma membrane transport
negative regulation of anion channel activity
cytoplasmic sequestering of CFTR protein
negative regulation of protein localization to cell surface
spermatid nucleus differentiation
regulation of catalytic activity
Sources:Amigo / QuickGO
Orthologs
Species
Human
Mouse
Entrez
57120
94221
Ensembl
ENSG00000047932
ENSMUSG00000019861
UniProt
Q9HD26
Q8BH60
RefSeq (mRNA)
NM_020399 NM_001017408
NM_001199272 NM_053187
RefSeq (protein)
NP_001017408 NP_065132
NP_001186201 NP_444417
Location (UCSC)
Chr 6: 117.56 – 117.6 Mb
Chr 10: 52.21 – 52.26 Mb
PubMed search
[3]
[4]
Wikidata
View/Edit Human
View/Edit Mouse
Golgi-associated PDZ and coiled-coil motif-containing protein is a protein that in humans is encoded by the GOPC gene.[5][6][7]
PIST is a PDZ domain-containing Golgi protein. PDZ domains contain approximately 90 amino acids and bind the extreme C terminus of proteins in a sequence-specific manner.[supplied by OMIM][7]
^ abcGRCh38: Ensembl release 89: ENSG00000047932 – Ensembl, May 2017
^ abcGRCm38: Ensembl release 89: ENSMUSG00000019861 – Ensembl, May 2017
^"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^Neudauer CL, Joberty G, Macara IG (Feb 2001). "PIST: a novel PDZ/coiled-coil domain binding partner for the rho-family GTPase TC10". Biochem Biophys Res Commun. 280 (2): 541–7. doi:10.1006/bbrc.2000.4160. PMID 11162552.
^Yao R, Maeda T, Takada S, Noda T (Aug 2001). "Identification of a PDZ domain containing Golgi protein, GOPC, as an interaction partner of frizzled". Biochem Biophys Res Commun. 286 (4): 771–8. doi:10.1006/bbrc.2001.5430. PMID 11520064.
coiled-coil motif-containing protein is a protein that in humans is encoded by the GOPC gene. PIST is a PDZ domain-containing Golgi protein. PDZ domains contain...
Molecular structure of the PDZ domain included in the human GOPC (Golgi-associated PDZ and coiled-coil motif-containing protein) protein Identifiers Symbol...
transmembrane conductance regulator has been shown to interact with: DNAJC5, GOPC, PDZK1, PRKCE, SLC4A8, SNAP23, SLC9A3R1, SLC9A3R2, and STX1A, It is inhibited...
to be connected to the human disease process. Examples of these include Gopc, Hrb and Csnka2. There are thousands of genes which guide the process of...
expression may be regulated by MITF. RHOQ has been shown to interact with EXOC7, GOPC, PARD6B, WASL, CDC42EP2, TRIP10 and CDC42EP3. GRCh38: Ensembl release 89:...
humans is encoded by the CSPG5 gene. CSPG5 has been shown to interact with GOPC. GRCh38: Ensembl release 89: ENSG00000114646 – Ensembl, May 2017 GRCm38:...
X, Zhang J, Cao Z, Wu J, Shi Y (September 2006). "Solution structure of GOPC PDZ domain and its interaction with the C-terminal motif of neuroligin"....
X, Zhang J, Cao Z, Wu J, Shi Y (September 2006). "Solution structure of GOPC PDZ domain and its interaction with the C-terminal motif of neuroligin"....
antagonists of δ2-containing receptors. GRID2 has been shown to interact with GOPC, GRIK2, PTPN4 and GRIA1. A possible correlation between GRID2 and the pre-B...
TM2 regions of the trimer. ASIC3 has been shown to interact with LIN7B, GOPC and MAGI1. GRCh38: Ensembl release 89: ENSG00000213199 – Ensembl, May 2017...
Global Information
