GNA13 information

GNA13
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1SHZ, 1ZCB, 3AB3, 3CX6, 3CX7, 3CX8
Identifiers
Aliases	GNA13, G13, G protein subunit alpha 13, HG1N
External IDs	OMIM: 604406 MGI: 95768 HomoloGene: 55976 GeneCards: GNA13
Gene location (Human)
Chr.	Chromosome 17 (human)
End	65,056,740 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	109,292,195 bp
RNA expression pattern
	Top expressed in
	secondary oocyte; ; sperm; ; superficial temporal artery; ; trabecular bone; ; jejunal mucosa; ; visceral pleura; ; lower lobe of lung; ; amniotic fluid; ; parietal pleura; ; seminal vesicula;
	Top expressed in
	epithelium of stomach; ; right lung lobe; ; supraoptic nucleus; ; cumulus cell; ; left colon; ; stria vascularis; ; left lung; ; blood; ; mammillary body; ; crypt of lieberkuhn of small intestine;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	nucleotide binding; G-protein beta/gamma-subunit complex binding; type 1 angiotensin receptor binding; GTP binding; D5 dopamine receptor binding; signal transducer activity; metal ion binding; protein binding; guanyl nucleotide binding; G protein-coupled receptor binding; guanyl-nucleotide exchange factor activity; GTPase activity;
Cellular component	membrane; focal adhesion; melanosome; brush border membrane; heterotrimeric G-protein complex; extracellular exosome; nucleus; cytoplasm; cytosol; plasma membrane;
Biological process	cell differentiation; intracellular signal transduction; regulation of cell migration; adenylate cyclase-activating G protein-coupled receptor signaling pathway; positive regulation of cytosolic calcium ion concentration; small GTPase mediated signal transduction; in utero embryonic development; platelet activation; activation of phospholipase D activity; Rho protein signal transduction; angiogenesis; regulation of cell shape; branching involved in blood vessel morphogenesis; signal transduction; positive regulation of apoptotic process; regulation of small GTPase mediated signal transduction; G protein-coupled receptor signaling pathway; adenylate cyclase-modulating G protein-coupled receptor signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	10672
	14674
	ENSG00000120063
	ENSMUSG00000020611
	Q14344
	P27601
	NM_001282425; NM_006572
	NM_010303; NM_001359034
	NP_001269354; NP_006563
	NP_034433; NP_001345963
	Wikidata
View/Edit Human	View/Edit Mouse

Guanine nucleotide-binding protein subunit alpha-13 is a protein that in humans is encoded by the GNA13 gene.^[5]^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000120063 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000020611 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Kabouridis PS, Waters ST, Escobar S, Stanners J, Tsoukas CD (Mar 1995). "Expression of GTP-binding protein alpha subunits in human thymocytes". Molecular and Cellular Biochemistry. 144 (1): 45–51. doi:10.1007/BF00926739. PMID 7791744. S2CID 8911988.
^ "Entrez Gene: GNA13 guanine nucleotide binding protein (G protein), alpha 13".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000120063 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000020611 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid7791744-5] Kabouridis PS, Waters ST, Escobar S, Stanners J, Tsoukas CD (Mar 1995). "Expression of GTP-binding protein alpha subunits in human thymocytes". Molecular and Cellular Biochemistry. 144 (1): 45–51. doi:10.1007/BF00926739. PMID 7791744. S2CID 8911988.

[entrez-6] "Entrez Gene: GNA13 guanine nucleotide binding protein (G protein), alpha 13".

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