GJD2 information

GJD2
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2N6A
Identifiers
Aliases	GJD2, CX36, GJA9, gap junction protein delta 2
External IDs	OMIM: 607058; MGI: 1334209; HomoloGene: 7734; GeneCards: GJD2; OMA:GJD2 - orthologs
Gene location (Human)
Chr.	Chromosome 15 (human)
End	34,754,998 bp
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)
End	113,844,100 bp
RNA expression pattern
	Top expressed in
	islet of Langerhans; ; pituitary gland; ; anterior pituitary; ; prefrontal cortex; ; body of pancreas; ; occipital lobe; ; dorsolateral prefrontal cortex; ; Brodmann area 9; ; cingulate gyrus; ; embryo;
	Top expressed in
	thoracic ganglia; ; islet of Langerhans; ; stellate ganglion; ; anterior horn of spinal cord; ; facial motor nucleus; ; pineal gland; ; olfactory bulb; ; retinal pigment epithelium; ; cerebellar cortex; ; sexually immature organism;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	gap junction channel activity;
Cellular component	integral component of membrane; gap junction; cell junction; plasma membrane; connexin complex; membrane;
Biological process	action potential; cell communication; cell-cell signaling; visual perception; chemical synaptic transmission; transmembrane transport;
	Sources:Amigo / QuickGO
Orthologs
	57369
	14617
	ENSG00000159248
	ENSMUSG00000068615
	Q9UKL4
	O54851
	NM_020660
	NM_010290
	NP_065711
	NP_034420
	Wikidata
View/Edit Human	View/Edit Mouse

Gap junction delta-2 protein (GJD2), also known as connexin-36 (Cx36) or gap junction alpha-9 protein (GJA9), is a protein that in humans is encoded by the GJD2 gene.^[5]^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000159248 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000068615 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Belluardo N, Trovato-Salinaro A, Mudo G, Hurd YL, Condorelli DF (Oct 1999). "Structure, chromosomal localization, and brain expression of human Cx36 gene". J Neurosci Res. 57 (5): 740–52. doi:10.1002/(SICI)1097-4547(19990901)57:5<740::AID-JNR16>3.0.CO;2-Z. PMID 10462698. S2CID 496510.
^ "Entrez Gene: GJA9 gap junction protein, alpha 9, 36kDa".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000159248 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000068615 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid10462698-5] Belluardo N, Trovato-Salinaro A, Mudo G, Hurd YL, Condorelli DF (Oct 1999). "Structure, chromosomal localization, and brain expression of human Cx36 gene". J Neurosci Res. 57 (5): 740–52. doi:10.1002/(SICI)1097-4547(19990901)57:5<740::AID-JNR16>3.0.CO;2-Z. PMID 10462698. S2CID 496510.

[entrez-6] "Entrez Gene: GJA9 gap junction protein, alpha 9, 36kDa".

GJD2 information

and 19 Related for: GJD2 information

GJD2

GJD3

Aquaporin

TRPV1

Sodium channel

Ion channel

Transient receptor potential channel

Pacemaker current

Membrane transport protein

Cystic fibrosis transmembrane conductance regulator

Ryanodine receptor

HCN channel

Inositol trisphosphate receptor

Connexin

ASIC4

Connexon

ROMK

Mechanosensitive channels

Potassium channel