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Final maturation induction information


Induction of final maturation of oocytes is a procedure that is usually performed as part of controlled ovarian hyperstimulation to render the oocytes fully developed and thereby resulting in optimal pregnancy chances. It is basically a replacement for the luteinizing hormone (LH) surge whose effects include final maturation in natural menstrual cycles.

The main medications used for induction of final maturation are human chorionic gonadotropin (hCG) and GnRH agonist. In fresh (rather than frozen) autologous cycles of in vitro fertilization, final oocyte maturation triggering with GnRH agonist instead of hCG decreases the risk of ovarian hyperstimulation syndrome but decreases live birth rate. In cycles followed by oocyte donation, use of GnRH agonists instead of hCG decreases the risk of ovarian hyperstimulation syndrome with no evidence of a difference in live birth rate.[1]

  1. ^ Cite error: The named reference YoussefVan der Veen2014 was invoked but never defined (see the help page).

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Final maturation induction

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Induction of final maturation of oocytes is a procedure that is usually performed as part of controlled ovarian hyperstimulation to render the oocytes...

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Ovulation induction

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anovulation or oligoovulation. The term ovulation induction can potentially also be used for: Final maturation induction, in the sense of triggering oocyte release...

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In vitro fertilisation

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pregnancy chances in IVF. Progesterone elevation on the day of induction of final maturation is associated with lower pregnancy rates in IVF cycles in women...

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Oocyte cryopreservation

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stimulate ovaries to ripen multiple eggs. When the eggs are mature, final maturation induction is performed, preferably by using a GnRH agonist rather than human...

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Fertility medication

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followed by embryo transfer of a maximum of two embryos at a time. Final maturation induction of follicles, also triggering a predictable time of ovulation...

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Human chorionic gonadotropin

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Human chorionic gonadotropin injection is extensively used for final maturation induction in lieu of luteinizing hormone. In the presence of one or more...

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Controlled ovarian hyperstimulation

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gonadotropin administration. Its duration can then be from 3 days to final maturation induction. A long GnRH agonist protocol has been associated with a higher...

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Fertility preservation

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with cancer is an antagonist protocol using a GnRH agonist for final maturation induction, in order to decrease the risk of OHSS. When used in conjunction...

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Ovarian stimulation

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stimulation may refer to: Ovulation induction, reversing anovulation or oligoovulation Final maturation induction of oocytes Controlled ovarian hyperstimulation...

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Delayed puberty

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is appropriate for bone age, meaning that they have delayed skeletal maturation with potential for future growth. It is often difficult to establish if...

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Capacitation

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either in vivo or in vitro capacitation the sperm must undergo the final maturation step, activation, involving the acrosome reaction. Non-mammalian spermatozoa...

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Development of the nervous system

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a non-invasive technique used to investigate myelination and cortical maturation (the cortex is the outer layer of the brain composed of gray matter)....

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Haematopoiesis

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granulocytes, except mast cells which are granulocytes but with an extramedullar maturation. Thrombopoiesis is haematopoiesis of thrombocytes (platelets). Between...

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Progesterone elevation

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Specifically, a progesterone level above 0.8 ng/ml on the day of induction of final maturation, as a biomarker in in vitro fertilization This disambiguation...

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Ovarian hyperstimulation syndrome

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Also, coasting, which is ovarian hyperstimulation without induction of final maturation, does not significantly decrease the risk of OHSS. Volume expanders...

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Broodstock

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female species often fail final oocyte maturation stage. Hormonal manipulation and acceleration of final oocyte maturation due to the economics of broodstock...

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Nodal signaling pathway

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growth factor beta (TGFβ) superfamily, is responsible for mesoendoderm induction, patterning of the nervous system, and determination of dorsal- ventral...

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Aromatase inhibitor

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associated with the use of aromatase inhibitors include decreased rate of bone maturation and growth, infertility, aggressive behavior, adrenal insufficiency, kidney...

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Reprogramming

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the maturation phase and achieve pluripotency. Some cells that undergo reprogramming still remain under apoptosis at the beginning of the maturation stage...

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Bacteriophage AP205

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protein shell also includes a single copy of a maturation protein (A protein) that functions in maturation of the virus and pilus attachment in prokaryotes...

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Inflorescence

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acropetal maturation. When flowers start to mature from the top of the stem, maturation is basipetal, whereas when the central mature first, maturation is divergent...

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Critical thinking

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States. If the development of critical-thinking skills was solely due to maturation, it is unlikely we would see such dramatic differences across cultures...

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Thymocyte

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the double positive stage (positive for both CD4 and CD8). The final stage in maturation is the single positive stage (positive for either CD4 or CD8)...

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Developmental biology

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doi:10.1242/dev.015701. PMID 18952908. Farge, Emmanuel (2003). "Mechanical induction of twist in the Drosophila foregut/stomodeal primordium". Current Biology...

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Transvaginal oocyte retrieval

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follicles have reached a certain degree of development, induction of final oocyte maturation is performed, generally by an intramuscular or subcutaneous...

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Micropropagation

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designed to encourage rapid growth. Due to the controlled nature of their maturation, the plantlets often do not have fully functional dermal coverings. This...

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Gonadotropin preparations

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an immune response in non-horse species. In Women: Used to induce final maturation of follicle and subsequent ovulation.[medical citation needed] Also...

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