FOSL1 information

FOSL1
Identifiers
Aliases	FOSL1, FRA, FRA1, fra-1, FOS like 1, AP-1 transcription factor subunit
External IDs	OMIM: 136515; MGI: 107179; HomoloGene: 3967; GeneCards: FOSL1; OMA:FOSL1 - orthologs
Gene location (Human)
Chr.	Chromosome 11 (human)
End	65,900,573 bp
Gene location (Mouse)
Chr.	Chromosome 19 (mouse)
End	5,505,974 bp
RNA expression pattern
	Top expressed in
	stromal cell of endometrium; ; gallbladder; ; vena cava; ; mucosa of urinary bladder; ; islet of Langerhans; ; ascending aorta; ; cervix epithelium; ; left uterine tube; ; skin of abdomen; ; upper lobe of left lung;
	Top expressed in
	supraoptic nucleus; ; lip; ; ascending aorta; ; calvaria; ; esophagus; ; stomach; ; yolk sac; ; visual cortex; ; zone of skin; ; cerebellar cortex;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	DNA binding; RNA polymerase II transcription regulatory region sequence-specific DNA binding; DNA-binding transcription factor activity; DNA-binding transcription activator activity, RNA polymerase II-specific; protein binding; RNA polymerase II cis-regulatory region sequence-specific DNA binding; DNA-binding transcription factor activity, RNA polymerase II-specific;
Cellular component	cytosol; intracellular membrane-bounded organelle; neuron projection; presynaptic membrane; nucleus; nucleoplasm;
Biological process	cellular response to extracellular stimulus; response to cytokine; regulation of transcription, DNA-templated; response to organic cyclic compound; vitellogenesis; regulation of transcription by RNA polymerase II; response to progesterone; female pregnancy; response to corticosterone; response to mechanical stimulus; response to virus; positive regulation of DNA-binding transcription factor activity; placenta blood vessel development; in utero embryonic development; learning; positive regulation of DNA-templated transcription, initiation; chemotaxis; response to gravity; cellular defense response; positive regulation of cell cycle; positive regulation of cell population proliferation; positive regulation of apoptotic process; response to cAMP; response to hydrogen peroxide; positive regulation of transcription by RNA polymerase II; negative regulation of cell population proliferation; pri-miRNA transcription by RNA polymerase II; transcription by RNA polymerase II;
	Sources:Amigo / QuickGO
Orthologs
	8061
	14283
	ENSG00000175592
	ENSMUSG00000024912
	P15407
	P48755
	NM_001300844; NM_001300855; NM_001300856; NM_001300857; NM_005438
	NM_010235
	NP_001287773; NP_001287784; NP_001287785; NP_001287786; NP_005429
	NP_034365
	Wikidata
View/Edit Human	View/Edit Mouse

Fos-related antigen 1 (FRA1) is a protein that in humans is encoded by the FOSL1 gene.^[5]^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000175592 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000024912 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Matsui M, Tokuhara M, Konuma Y, Nomura N, Ishizaki R (Mar 1990). "Isolation of human fos-related genes and their expression during monocyte-macrophage differentiation". Oncogene. 5 (3): 249–255. PMID 2107490.
^ "Entrez Gene: FOSL1 FOS-like antigen 1".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000175592 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000024912 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid2107490-5] Matsui M, Tokuhara M, Konuma Y, Nomura N, Ishizaki R (Mar 1990). "Isolation of human fos-related genes and their expression during monocyte-macrophage differentiation". Oncogene. 5 (3): 249–255. PMID 2107490.

[entrez-6] "Entrez Gene: FOSL1 FOS-like antigen 1".

FOSL1 information

and 23 Related for: FOSL1 information

FOSL1

Fos

List of human transcription factors

Homeobox

FOSB

Zinc finger

CREB

Zbtb7

FOXP2

Estrogen receptor

Androgen receptor

Hormone receptor

Retinoblastoma protein

Sigma factor

Heterochromatin protein 1

Glucocorticoid receptor

Myc

Retinoid X receptor

General transcription factor

SPI1

Steroid hormone receptor

NFE2L2

HIF1A