FANCG information

FANCG
Identifiers
Aliases	FANCG, FAG, XRCC9, Fanconi anemia complementation group G, FA complementation group G
External IDs	OMIM: 602956; MGI: 1926471; HomoloGene: 3402; GeneCards: FANCG; OMA:FANCG - orthologs
Gene location (Human)
Chr.	Chromosome 9 (human)
End	35,080,004 bp
Gene location (Mouse)
Chr.	Chromosome 4 (mouse)
End	43,010,506 bp
RNA expression pattern
	Top expressed in
	ventricular zone; ; ganglionic eminence; ; right hemisphere of cerebellum; ; mucosa of transverse colon; ; granulocyte; ; body of pancreas; ; left testis; ; right testis; ; rectum; ; right frontal lobe;
	Top expressed in
	spermatocyte; ; aortic valve; ; neural layer of retina; ; spermatid; ; ascending aorta; ; yolk sac; ; seminiferous tubule; ; cumulus cell; ; granulocyte; ; thymus;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	damaged DNA binding; protein binding; signal transducer activity;
Cellular component	plasma membrane; nucleolus; Fanconi anaemia nuclear complex; mitochondrion; nucleus; nucleoplasm; cytoplasm; cytosol; intracellular anatomical structure;
Biological process	ovarian follicle development; response to radiation; mitochondrion organization; interstrand cross-link repair; DNA repair; spermatid development; cellular response to DNA damage stimulus; phosphorelay signal transduction system;
	Sources:Amigo / QuickGO
Orthologs
	2189
	60534
	ENSG00000221829
	ENSMUSG00000028453
	O15287
	Q9EQR6
	NM_004629
	NM_001163233; NM_053081
	NP_004620
	NP_001156705; NP_444311
	Wikidata
View/Edit Human	View/Edit Mouse

Fanconi anemia group G protein is a protein that in humans is encoded by the FANCG gene.^[5]^[6]^[7]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000221829 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000028453 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Liu N, Lamerdin JE, Tucker JD, Zhou ZQ, Walter CA, Albala JS, Busch DB, Thompson LH (Sep 1997). "The human XRCC9 gene corrects chromosomal instability and mutagen sensitivities in CHO UV40 cells". Proc Natl Acad Sci U S A. 94 (17): 9232–7. Bibcode:1997PNAS...94.9232L. doi:10.1073/pnas.94.17.9232. PMC 23130. PMID 9256465.
^ Joenje H, Oostra AB, Wijker M, di Summa FM, van Berkel CG, Rooimans MA, Ebell W, van Weel M, Pronk JC, Buchwald M, Arwert F (Nov 1997). "Evidence for at least eight Fanconi anemia genes". Am J Hum Genet. 61 (4): 940–4. doi:10.1086/514881. PMC 1715980. PMID 9382107.
^ "Entrez Gene: FANCG Fanconi anemia, complementation group G".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000221829 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000028453 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid9256465-5] Liu N, Lamerdin JE, Tucker JD, Zhou ZQ, Walter CA, Albala JS, Busch DB, Thompson LH (Sep 1997). "The human XRCC9 gene corrects chromosomal instability and mutagen sensitivities in CHO UV40 cells". Proc Natl Acad Sci U S A. 94 (17): 9232–7. Bibcode:1997PNAS...94.9232L. doi:10.1073/pnas.94.17.9232. PMC 23130. PMID 9256465.

[pmid9382107-6] Joenje H, Oostra AB, Wijker M, di Summa FM, van Berkel CG, Rooimans MA, Ebell W, van Weel M, Pronk JC, Buchwald M, Arwert F (Nov 1997). "Evidence for at least eight Fanconi anemia genes". Am J Hum Genet. 61 (4): 940–4. doi:10.1086/514881. PMC 1715980. PMID 9382107.

[entrez-7] "Entrez Gene: FANCG Fanconi anemia, complementation group G".

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