FANCF information

FANCF
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2IQC
Identifiers
Aliases	FANCF, FAF, Fanconi anemia complementation group F, FA complementation group F
External IDs	OMIM: 613897 MGI: 3689889 HomoloGene: 75185 GeneCards: FANCF
Gene location (Human)
Chr.	Chromosome 11 (human)
End	22,625,823 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	51,512,015 bp
RNA expression pattern
	Top expressed in
	secondary oocyte; ; endothelial cell; ; bronchial epithelial cell; ; ganglionic eminence; ; corpus epididymis; ; caput epididymis; ; hair follicle; ; islet of Langerhans; ; body of pancreas; ; jejunal mucosa;
	Top expressed in
	trigeminal ganglion; ; condyle; ; fossa; ; Paneth cell; ; renal corpuscle; ; barrel cortex; ; substantia nigra; ; motor neuron; ; medullary collecting duct; ; internal carotid artery;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein binding; molecular function; ubiquitin protein ligase activity;
Cellular component	Fanconi anaemia nuclear complex; nucleus; nucleoplasm;
Biological process	interstrand cross-link repair; cellular response to DNA damage stimulus; DNA repair; biological process; ovarian follicle development; spermatogenesis; protein ubiquitination;
	Sources:Amigo / QuickGO
Orthologs
	2188
	100040608
	ENSG00000183161
	ENSMUSG00000092118
	Q9NPI8
	E9Q5Z5
	NM_022725
	NM_001115087
	NP_073562
	NP_001108559
	Wikidata
View/Edit Human	View/Edit Mouse

Fanconi anemia group F protein is a protein that in humans is encoded by the FANCF gene.^[5]^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000183161 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000092118 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Joenje H, Oostra AB, Wijker M, di Summa FM, van Berkel CG, Rooimans MA, Ebell W, van Weel M, Pronk JC, Buchwald M, Arwert F (October 1997). "Evidence for at least eight Fanconi anemia genes". American Journal of Human Genetics. 61 (4): 940–4. doi:10.1086/514881. PMC 1715980. PMID 9382107.
^ "Entrez Gene: FANCF Fanconi anemia, complementation group F".

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