Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Chemical compound
Equol (4',7-isoflavandiol) is an isoflavandiol[1] estrogen metabolized from daidzein, a type of isoflavone found in soybeans and other plant sources, by bacterial flora in the intestines.[2][3] While endogenous estrogenic hormones such as estradiol are steroids, equol is a nonsteroidal estrogen. Only about 30–50% of people have intestinal bacteria that make equol.[4]
^The structures of 7,4’-dihydroxy-isoflavan and its precursors is shown in Structural Elucidation of Hydroxylated Metabolites of the Isoflavan Equol by GC/MS and HPLC/MS by Corinna E. Rüfer, Hansruedi Glatt, and Sabine E. Kulling in Drug Metabolism and Disposition (2005, electronic publication).
^Wang XL, Hur HG, Lee JH, Kim KT, Kim SI (January 2005). "Enantioselective synthesis of S-equol from dihydrodaidzein by a newly isolated anaerobic human intestinal bacterium". Appl. Environ. Microbiol. 71 (1): 214–9. Bibcode:2005ApEnM..71..214W. doi:10.1128/AEM.71.1.214-219.2005. PMC 544246. PMID 15640190.
^Muthyala, Rajeev S; Ju, Young H; Sheng, Shubin; Williams, Lee D; Doerge, Daniel R; Katzenellenbogen, Benita S; Helferich, William G; Katzenellenbogen, John A (2004). "Equol, a natural estrogenic metabolite from soy isoflavones". Bioorganic & Medicinal Chemistry. 12 (6): 1559–1567. doi:10.1016/j.bmc.2003.11.035. ISSN 0968-0896. PMID 15018930.
^Frankenfeld CL, Atkinson C, Thomas WK, et al. (December 2005). "High concordance of daidzein-metabolizing phenotypes in individuals measured 1 to 3 years apart". Br. J. Nutr. 94 (6): 873–6. doi:10.1079/bjn20051565. PMID 16351761.
Equol (4',7-isoflavandiol) is an isoflavandiol estrogen metabolized from daidzein, a type of isoflavone found in soybeans and other plant sources, by...
3-phenylchroman (isoflavan) backbone (case of isoflavanes, such as equol). Daidzein Equol Flavonoid Genistein Glycitein Homoisoflavonoids, related molecules...
The Paper. 2021-01-07. "Stinky tofu as a rich source of bioavailable S-equol in Asian diets". ResearchGate. 13 April 2013. "Yongfeng chili sauce". cgi...
from a rat caecum in Japan. Asaccharobacter celatus produces equol and 5-hydroxy equol. In 2018, the genus Asaccharobacter was transferred into the genus...
Adlercreutzia equolifaciens is a equol-producing bacterium from the genus of Adlercreutzia which has been isolated from human faeces. The species Adlercreutzia...
Skin Care is equol. The topical effect of equol as an anti-aging and skin health improving substance was shown in different studies. Equol can occur as...
effects with intakes up to 150 mg/d, although it criticized the lack of data. Equol Glycitein Isoflavonoid Phytochemical Rotenoids "Soy isoflavones". Micronutrient...
Braune, A (January 2012). "Daidzein and genistein are converted to equol and 5-hydroxy-equol by human intestinal Slackia isoflavoniconvertens in gnotobiotic...
product of daidzein microbial metabolism is equol. Only 33% of Western Europeans have a microbiome that produces equol, compared to 50–55% of Asians. Soy...
associated with menopause, was launched in 2019. The supplement relies on S-equol, an intestinal bacterial metabolite of isoflavone daidzein2 that binds to...
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