Equine chorionic gonadotropin (acronym given as eCG but not to be confused with ECG) is a gonadotropic hormone produced in the chorion of pregnant mares. Previously referred to as pregnant mare's serum gonadotropin (PMSG), the hormone is commonly used in concert with progestogen to induce ovulation in livestock prior to artificial insemination.
Pregnant mares secrete the hormone from their endometrial cups between 40 and 130 days into their gestation, and once collected, it has been used to artificially induce estrus in female sheep, goats, cattle, and swine. Despite being less pure than pituitary extracts from sheep, goats or swine, PMSG tends to be used because of its longer circulatory half-life. In equids PMSG has only LH like activity, but in other species it has activity like both follicle-stimulating hormone (FSH) and luteinizing hormone (LH).
Equine CG, like all glycoprotein hormones, is composed of two dissimilar subunits named alpha and beta. The alpha subunit is common to all glycoprotein hormones (LH, FSH, TSH, CG). The beta subunits are hormone-specific and are responsible for receptor binding specificity, although CG binds to the same luteinizing hormone/choriogonadotropin receptor as LH. In the equids (horses, donkeys, zebras), the placental CGs and pituitary LH are expressed from the same gene and thus have the same protein sequence, differing only by their carbohydrate side-chains (particularly in their respective beta subunits).
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hormone (LH), the placental/chorionicgonadotropins, human chorionicgonadotropin (hCG) and equinechorionicgonadotropin (eCG), as well as at least two...
Equinechorionicgonadotropin (acronym given as eCG but not to be confused with ECG) is a gonadotropic hormone produced in the chorion of pregnant mares...
Human chorionicgonadotropin (hCG) is a hormone for the maternal recognition of pregnancy produced by trophoblast cells that are surrounding a growing...
(2014-08-01). "The Use of Equine Follicle Stimulating Hormone to Increase EquineChorionicGonadotropin in the Pregnant Mare". Journal of Equine Veterinary Science...
costly; it also has a longer half-life. In veterinary medicine, equinechorionicgonadotropin (eCG) extracted from pregnant mare serum is used instead on...
secreting progesterone eCG – equinechorionicgonadotropin – also called PMSG (pregnant mare serum gonadotropin): chorionicgonadotropins secreted if the mare...
Endometrial cups form during pregnancy in mares and are the source of equinechorionicgonadotropin (eCG) and a placenta-associated structure, which is derived...
1992). "A single gene encodes the beta-subunits of equine luteinizing hormone and chorionicgonadotropin". Mol. Endocrinol. 6 (6): 951–9. doi:10.1210/mend...
preferred hormone in cattle, sheep and goats. While in pigs, equinechorionicgonadotropin is preferred. However, this is not commonly done in the swine...
names Ovuplant, SucroMate, and Suprelorin among others, is an injectable gonadotropin releasing hormone superagonist (GnRH agonist) which is used in veterinary...
The first hormone released by the placenta is called the human chorionicgonadotropin (hCG) hormone. This is responsible for stopping the process at the...
systemic effects. Some teratomas secrete the "pregnancy hormone" human chorionicgonadotropin (βhCG), which can be used in clinical practice to monitor the successful...
lower incidence of breast cancer in post-hysterectomy participants taking equine estrogen alone, though the relative risk was increased if estrogen was taken...
the oocytes are primed with follicle-stimulating hormone (FSH) or human chorionic gonadotrophin (hCG) before retrieval. hCG is important in women with polycystic...
course of testosterone-boosting therapy (e.g. clomifene and human chorionicgonadotropin) usually results in return to normal testosterone production.) Female-specific...
producing the more-easily manufactured conjugated[clarification needed] equine estrogens in 1941 under the brand name Premarin; by 1992, Premarin was the...
pregnancy. Blood tests for alpha-fetoprotein, karyotype, human chorionicgonadotropin, and liver function are used to diagnose germ cell tumor and potential...
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