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Epilepsy surgery
Specialty
neurology, neurosurgery, epileptology
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Epilepsy surgery involves a neurosurgical procedure where an area of the brain involved in seizures is either resected, ablated, disconnected or stimulated.[1] The goal is to eliminate seizures or significantly reduce seizure burden. Approximately 60% of all people with epilepsy (0.4% of the population of industrialized countries) have focal epilepsy syndromes. In 15% to 20% of these patients, the condition is not adequately controlled with anticonvulsive drugs. Such patients are potential candidates for surgical epilepsy treatment.
First line therapy for epilepsy involves treatment with anticonvulsive drugs, also called antiepileptic drugs. Most patients will respond to one or two different medication trials. The goal of this treatment is the elimination of seizures, since uncontrolled seizures carry significant risks, including injury and sudden death. However, in up to one third of patients, medications alone do not eliminate seizures, and/or cause adverse effects. In these patients, epilepsy surgery is considered as an alternate treatment method to medications.
Generally, surgery is considered in patients whose seizures cannot be controlled by adequate trials of two different medications. Epilepsy surgery has been performed for more than a century, but its use dramatically increased in the 1980s and 1990s, reflecting its efficacy in selected patients.[2][3]
^Jobst BC, Cascino GD (2015). "Resective epilepsy surgery for drug-resistant focal epilepsy: a review". JAMA. 313 (3): 285–93. doi:10.1001/jama.2014.17426. PMID 25602999.
^Spencer SS, Berg AT, Vickrey BG, et al. (December 2003). "Initial outcomes in the Multicenter Study of Epilepsy Surgery". Neurology. 61 (12): 1680–5. doi:10.1212/01.WNL.0000098937.35486.A3. PMID 14694029. S2CID 21481756.
^Krucoff, Max O.; Chan, Alvin Y.; Harward, Stephen C.; Rahimpour, Shervin; Rolston, John D.; Muh, Carrie; Englot, Dario J. (December 2017). "Rates and predictors of success and failure in repeat epilepsy surgery: A meta-analysis and systematic review". Epilepsia. 58 (12): 2133–2142. doi:10.1111/epi.13920. ISSN 1528-1167. PMC 5716856. PMID 28994113.
Epilepsysurgery involves a neurosurgical procedure where an area of the brain involved in seizures is either resected, ablated, disconnected or stimulated...
Anticonvulsant medications, epilepsysurgery and dietary treatments may improve seizure control. Under the International League Against Epilepsy (ILAE) 2017 classification...
not respond to medication; surgery, neurostimulation or dietary changes may then be considered. Not all cases of epilepsy are lifelong, and many people...
electrical stimulation during ECoG recordings in patients undergoing epilepsysurgery under local anesthesia. This procedure was used to explore the functional...
Sudden unexpected death in epilepsy (SUDEP) is a fatal complication of epilepsy. It is defined as the sudden and unexpected, non-traumatic and non-drowning...
disease, epilepsy, and cerebellar tremor. The procedure is also used in epilepsysurgery to remove the parts of the brain that are causing epilepsy. Craniotomy...
lobe epilepsysurgery have hippocampal sclerosis.: 1316 About 7% of those with temporal lobe epilepsy have familial mesial temporal lobe epilepsy, and...
epilepsy with the first drug they use, whereas around 30% do not achieve control with drugs. When drugs fail, other options include epilepsysurgery,...
endarterectomy (CEA). Stereotactic neurosurgery, functional neurosurgery, and epilepsysurgery (the latter includes partial or total corpus callosotomy – severing...
Frontal lobe epilepsy (FLE) is a neurological disorder that is characterized by brief, recurring seizures arising in the frontal lobes of the brain, that...
An epilepsy syndrome is defined as "a characteristic cluster of clinical and EEG features, often supported by specific etiological findings (structural...
Neurological Surgeons. Attempting to treat epilepsy, van Wagenen studied and published the results of his surgeries, including the split-brain outcomes for...
curve recordings and epilepsysurgery, which are nationwide concentrated in Kuopio and Helsinki, but most of Finland's epilepsy surgical procedures are...
patient to the other. The test is usually performed prior to ablative surgery for epilepsy and sometimes prior to tumor resection. The aim is to determine which...
and Treatment of Epilepsy: A Practical Guide. Elsevier Science. ISBN 9780080529462. Lüders, H.; Comair, Y.G. (2001). EpilepsySurgery. Lippincott Williams...
stimulation but not epilepsysurgery. The ketogenic diet is a high fat, low carbohydrate diet reserved for intractable childhood epilepsies. There are no published...
Neurosciences des Systèmes. He is the coordinator of the "Improving Epilepsysurgery management and prognosis using Virtual brain technology" (EPINOV) project...
used to treat the seizures that may arise due to cortical dysplasia. Epilepsysurgery to remove areas of FCD is a viable treatment option for appropriate...
of neurology at Northwell Health specializing in the field of epilepsy, epilepsysurgery and neuro-imaging. He was one of the first to recognize and prove...
condition epilepsy. Following from that, there is a short list of people who have received a speculative, retrospective diagnosis of epilepsy. Finally...
physically removed from the skull. This surgery is mostly used as a treatment for medically intractable epilepsy, which is the term used when anti-seizure...
for epilepsy include medications, diet, and surgery. Diet and surgery are considered for children who have medication resistant epilepsy. Epilepsy is classified...
classify postoperative outcomes for epilepsysurgery, Jerome Engel proposed the following scheme, the Engel EpilepsySurgery Outcome Scale, which has become...
and staff physician in Cleveland Clinic's Epilepsy Center. Her research focuses on the role of epilepsysurgery in children with drug-resistant seizures...
medications and that the patient is ineligible for epilepsysurgery. This is because epilepsysurgery is associated with a higher probability of resulting...
provide some prognostic information. If a patient with epilepsy is being considered for resective surgery, it is often necessary to localize the focus (source)...
temporal lobe epilepsy – An overview of surgical techniques". International Journal of Surgery. Epilepsysurgery for pharmacoresistant epilepsy. 36 (Pt B):...
establishing cerebral dominance and is conducted worldwide prior to epilepsysurgery. Wada was a professor in the Department of Psychiatry and Neurosciences...
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