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Corpus callosotomy information


Corpus callosotomy
Specialtyneurology
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Corpus callosotomy is a palliative surgical procedure for the treatment of medically refractory epilepsy.[1] In this procedure the corpus callosum is cut through, in an effort to limit the spread of epileptic activity between the two halves of the brain.[1]

After the operation, the brain has much more difficulty sending messages between the hemispheres. Although the corpus callosum is the largest white matter tract connecting the hemispheres, some limited interhemispheric communication is still possible via the anterior commissure and posterior commissure.

"Efficacy and relatively low permanent morbidity in corpus callosotomy for medically intractable epilepsy have been demonstrated by more than six decades of experience. In addition to seizure reduction, behavior and quality of life may improve."[2]

  1. ^ a b Mathews, Marlon S.; Linskey, Mark E.; Binder, Devin K. (2008-02-29). "William P. van Wagenen and the first corpus callosotomies for epilepsy". Journal of Neurosurgery. 108 (3): 608–613. doi:10.3171/JNS/2008/108/3/0608. ISSN 0022-3085. PMID 18312112. S2CID 6007475.
  2. ^ Asadi-Pooya, Ali A.; Sharan, Ashwini; Nei, Maromi; Sperling, Michael R. (2008). "Corpus callosotomy". Epilepsy & Behavior. 13 (2): 271–8. doi:10.1016/j.yebeh.2008.04.020. PMID 18539083. S2CID 19256444.

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