The epigenetic code is hypothesised to be a defining code in every eukaryotic cell consisting of the specific epigenetic modification in each cell. It consists of histone modifications defined by the histone code and additional epigenetic modifications such as DNA methylation. The base for the epigenetic code is a system above the genetic code of a single cell. While in one individual the genetic code in each cell is the same, the epigenetic code is tissue and cell specific.[1] The epigenetic code can be multidimensional in nature. It could include any of the three major cellular macromolecucles; namely, DNA (code independent), RNA, and/or protein. In some ciliates potential structural codes have also been suggested.[2]
^Turner B (2007). "Defining an epigenetic code". Nature Cell Biology. 9 (1): 2–6. doi:10.1038/ncb0107-2. PMID 17199124.
^Chahwan R, Wontakal SN, Roa S (March 2011). "The multidimensional nature of epigenetic information and its role in disease". Discov Med. 11 (58): 233–43. PMID 21447282.{{cite journal}}: CS1 maint: multiple names: authors list (link)
The epigeneticcode is hypothesised to be a defining code in every eukaryotic cell consisting of the specific epigenetic modification in each cell. It...
In biology, epigenetics is the study of heritable traits, or a stable change of cell function, that happen without changes to the DNA sequence. The Greek...
Transgenerational epigenetic inheritance is the transmission of epigenetic markers and modifications from one generation to multiple subsequent generations...
with similar modifications such as DNA methylation it is part of the epigeneticcode. Histones associate with DNA to form nucleosomes, which themselves...
without changing the coding sequence. Epigenetic therapy involves using drugs or other techniques to influence these epigenetic mechanisms in addressing...
plant kingdom, this is doubly so, since alterations to the genetic and epigeneticcode will be more easily inherited. While transposable elements may affect...
modifications such as DNA methylation it is part of the epigeneticcode. Cumulative evidence suggests that such code is written by specific enzymes which can (for...
Computational epigenetics uses statistical methods and mathematical modelling in epigenetic research. Due to the recent explosion of epigenome datasets...
and non-coding RNA. The development of sleep disorders such as insomnia, sleep apnea, and narcolepsy can be greatly impacted by epigenetic changes. Additionally...
An epigenetic clock is a biochemical test that can be used to measure age. The test is based on DNA methylation levels, measuring the accumulation of methyl...
sequence, but instead involve a change in the way the genetic code is expressed. Epigenetic mechanisms are necessary to maintain normal sequences of tissue...
Retrieved 9 November 2015. Richards, Eric J.; Elgin, Sarah C. R. (2002). "EpigeneticCodes for Heterochromatin Formation and Silencing". Cell. 108 (4): 489–500...
Epigenomics is the study of the complete set of epigenetic modifications on the genetic material of a cell, known as the epigenome. The field is analogous...
(March 2003). "Histone deacetylases: unique players in shaping the epigenetic histone code". Annals of the New York Academy of Sciences. 983 (1): 84–100....
completeness. This is particularly challenging because the genome-wide epigeneticcode must be reformatted to that of the target cell type in order to fully...
Epigenetics of physical exercise is the study of epigenetic modifications to the cell genome resulting from physical exercise. Environmental factors,...
The epigenetics of schizophrenia is the study of how inherited epigenetic changes are regulated and modified by the environment and external factors and...
Nutritional epigenetics is a science that studies the effects of nutrition on gene expression and chromatin accessibility. It is a subcategory of nutritional...
main mechanisms of epigenetic alterations are DNA methylation, histone modifications, and regulation by non-coding RNAs. These epigenetic changes regulate...
in gene regulation and expression. Noncoding RNA also contributes to epigenetics, transcription, RNA splicing, and the translational machinery. The role...
many epigenetic mechanisms are involved in the regulation and expression of genes such as DNA methylation and chromatin remodeling. These epigenetic mechanisms...
they are derived from the same cell, and all carry the same genetic or epigenetic anomaly – evident of clonality. For lymphoid neoplasms, e.g. lymphoma...
of transmission are the uterine environment during pregnancy causing epigenetic changes in the developing embryo, and the shared family environment of...
G. (2006-06-01). "Sensors and signals: a coactivator/corepressor/epigeneticcode for integrating signal-dependent programs of transcriptional response"...
turned to the epigenetic mechanisms behind the dynamic changes in gene transcription responsible for memory formation and maintenance. Epigenetic gene regulation...
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