Endophthalmitis, or endophthalmia, is inflammation of the interior cavity of the eye, usually caused by an infection. It is a possible complication of all intraocular surgeries, particularly cataract surgery, and can result in loss of vision or loss of the eye itself.[1] Infection can be caused by bacteria or fungi, and is classified as exogenous (infection introduced by direct inoculation as in surgery or penetrating trauma), or endogenous (organisms carried by blood vessels to the eye from another site of infection and is more common in people who have an immunocompromised state). Other non-infectious causes include toxins, allergic reactions, and retained intraocular foreign bodies. Intravitreal injections are a rare cause, with an incidence rate usually less than 0.05%.
Endophthalmitis requires immediate medical attention to ensure the condition is diagnosed as soon as possible and treatment is started in order to reduce the risk of the person losing vision in the eye.[2] Treatment options depend on the cause and whether the condition is cause by an endogenous or exogenous mechanism. For people with suspected exogenous endophthalmitis, a biopsy (virtuous tap) and treatment with antibiotics (usually by injection) is usually the first line of treatment.[2] Once the person's response to the antibiotics is assessed, different further treatment options may be considered including surgery.
^Oiseth S, Jones L, Maza E, eds. (10 November 2022). "Endophthalmitis". The Lecturio Medical Concept Library. Retrieved 19 July 2021.
^ abMuqit MM, Mehat M, Bunce C, Bainbridge JW, et al. (Cochrane Eyes and Vision Group) (November 2022). "Early vitrectomy for exogenous endophthalmitis following surgery". The Cochrane Database of Systematic Reviews. 2022 (11): CD013760. doi:10.1002/14651858.CD013760.pub2. PMC 9672977. PMID 36398614.
surgery. Symptoms of endophthalmitis include severe eye pain, vision loss, and intense redness of the conjunctiva. Bacterial endophthalmitis more commonly presents...
rabbit endophthalmitis models. Later, more studies proved the beneficial effects of intravitreal antibiotics on acute postoperative endophthalmitis. In the...
Incidence of endophthalmitis after intravitreal injection per patient has been reported to range from 0.019 to 1.6%. Endophthalmitis can also result...
cefuroxime after cataract surgery will lower the chance of developing endophthalmitis after surgery. Cefuroxime is generally well tolerated, and its side...
postoperative endophthalmitis caused by S. lugdunensis is infrequently reported in clinical studies. Five cases of acute postcataract surgery endophthalmitis were...
an antibiotic into the anterior chamber of the eyeball to prevent endophthalmitis caused by an infection of the eye that can occur after cataract surgery...
in a corneal ulcer. It can occur as a result of Behçet's disease, endophthalmitis, panuveitis/panophthalmitis, or adverse reactions to some drugs (such...
without discharge or tearing Uveitis Acute angle-closure glaucoma Endophthalmitis Orbital cellulitis The most effective prevention is good hygiene, especially...
yellow. It is known to cause ocular infections, brain abscesses, and endophthalmitis. "Kocuria varians". Global Biodiversity Information Facility. Retrieved...
vancomycin resistant E. faecium strains. In the context of preventing endophthalmitis, a complication of cataract surgery, a 2017 systematic review found...
patient with a chronic hepatitis B infection, and from an eye infection (endophthalmitis). The infection rate and morbidity of S. gallinarum is comparatively...
include retinal detachment and endophthalmitis. In both cases, patients notice a sudden decrease in vision. In endophthalmitis, patients often describe pain...
skin condition of acne; it can also cause chronic blepharitis and endophthalmitis, the latter particularly following intraocular surgery. Its genome...
differentiating toxic anterior segment syndrome from an infectious endophthalmitis is the rapid onset. Most patients with toxic anterior segment syndrome...
cataract surgery, has been found to lower the chance of developing endophthalmitis, compared to eye drops or injections alone. According to the FDA approved...
for these organs. E. casseliflavus has also been reported to cause endophthalmitis. Enterococcus casseliflavus are facultative Gram-positive cocci. They...
Oxalobacteraceae, which was isolated from a patient suffering from endophthalmitis. Its 16S rRNA gene sequence analysis has shown that it belongs to Massilia...
that caused by a corneal foreign body or keratitis Ectopia lentis Endophthalmitis Eye trauma caused by disease, injury, or infection such as chalazion...
2013. "Endophthalmitis". Lecturio. Archived from the original on 19 July 2021. Retrieved 19 July 2021. Bennett JE (8 August 2019). "Endophthalmitis". Mandell...
thereby limiting vision. Others may result in perforation of the cornea, endophthalmitis (an infection inside the eye), or even loss of the eye. With proper...
xerophilic species of fungus in the genus Aspergillus which can cause endophthalmitis in rare cases. It was first described in 1914. It is from the section...
Dexamethasone has also been used with antibiotics to treat acute endophthalmitis. Dexamethasone is used in transvenous screw-in cardiac pacing leads...
been found to be capable of causing endophthalmitis particularly in immune compromised patients. Endophthalmitis is an inflammatory response typically...
larva migrans (OLM) is the third syndrome, manifesting as uveitis, endophthalmitis, visual impairment or even blindness in the affected eye. Physiological...
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