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Intravitreal administration information


Intravitreal administration delivers substances directly into the vitreous chamber.

Intravitreal administration is a route of administration of a drug, or other substance, in which the substance is delivered into the vitreous humor of the eye. "Intravitreal" literally means "inside an eye". Intravitreal injections were first introduced in 1911 when Ohm gave an injection of air into the vitreous humor to repair a detached retina. In the mid-1940s, intravitreal injections became a standard way to administer drugs to treat endophthalmitis and cytomegalovirus retinitis.[1]

  1. ^ Grzybowski, Andrzej; Told, Reinhard; Sacu, Stefan; Bandello, Francesco; Moisseiev, Elad; Loewenstein, Anat; Schmidt-Erfurth, Ursula (May 2018). "2018 Update on Intravitreal Injections: Euretina Expert Consensus Recommendations". Ophthalmologica. Ophthalmologica 239 (4). 239 (4): 181–193. doi:10.1159/000486145. PMID 29393226. Retrieved 2020-05-02.

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Intravitreal administration

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Intravitreal administration is a route of administration of a drug, or other substance, in which the substance is delivered into the vitreous humor of...

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Intravitreal injection

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Intravitreal injection is the method of administration of drugs into the eye by injection with a fine needle. The medication will be directly applied into...

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Avacincaptad pegol

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number NCT04435366 for "A Phase 3 Safety and Efficacy Study of Intravitreal Administration of Zimura (Complement C5 Inhibitor)" at ClinicalTrials.gov Portal:...

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Intrathecal administration

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Intrathecal administration is a route of administration for drugs via an injection into the spinal canal, or into the subarachnoid space so that it reaches...

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Vitreomacular adhesion

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GA. de Smet MD, Gandorfer A, Stalmans P, et al. Microplasmin intravitreal administration in patients with vitreomacular traction scheduled for vitrectomy:...

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Adverum Biotechnologies

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Drug Designation to Adverum's ADVM-062, developed as a single intravitreal administration for blue-cone monochromacy by delivering a functional copy of...

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Triamcinolone acetonide

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dental paste preparations are used for treating aphthous ulcers. As an intravitreal injection, triamcinolone acetonide has been used to treat various eye...

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Route of administration

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parenteral nutrition. Intravesical infusion is into the urinary bladder. Intravitreal, through the eye. Subcutaneous (under the skin). This generally takes...

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Rectal administration

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Rectal administration (colloquially known as boofing or plugging) uses the rectum as a route of administration for medication and other fluids, which...

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Subcutaneous administration

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Subcutaneous administration is the insertion of medications beneath the skin either by injection or infusion. A subcutaneous injection is administered...

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Pegaptanib

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Aside from the intravitreal administration of the pegaptanib, it was also found that subcutaneous and intravenous routes of administration were also effective...

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Buccal administration

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Buccal administration is a topical route of administration by which drugs held or applied in the buccal (/ˈbʌkəl/) area (in the cheek) diffuse through...

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Sublingual administration

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administration by which substances diffuse into the blood through tissues under the tongue. Many drugs are absorbed through sublingual administration...

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Enteral administration

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administration is food or drug administration via the human gastrointestinal tract. This contrasts with parenteral nutrition or drug administration (Greek...

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Retinal vasculitis

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vitreous body) or choroiditis (inflammation of the choroid). Intravitreal administration of corticosteroid and immunosuppressants in a case non infectious...

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Sublabial administration

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Sublabial administration, literally "under the lip", from Latin, refers to the pharmacological route of administration by which the active substance is...

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Intracameral injection

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of the eye that can occur after cataract surgery. The Food and Drug Administration (FDA) has not approved antibiotics for this use and it is considered...

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Pegcetacoplan

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subcutaneous infusion for paroxysmal nocturnal hemoglobinuria and through intravitreal injection for age-related macular degeneration. Pegcetacoplan acts as...

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Epidural administration

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Epidural administration (from Ancient Greek ἐπί, "upon" + dura mater) is a method of medication administration in which a medicine is injected into the...

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Transdermal

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Transdermal is a route of administration wherein active ingredients are delivered across the skin for systemic distribution. Examples include transdermal...

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Conbercept

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(pmCNV), diabetic macular edema (DME). The medication is given through intravitreal injection (IVT). Conbercept is contraindicated in patients with known...

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Fluocinolone acetonide

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fold compared to the widely used dexamethasone. Fluocinolone acetonide intravitreal implants have been used to treat non-infectious uveitis. A systematic...

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Suppository

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uk. Retrieved 2021-12-11. Lowry, Michael (2016-02-22). "Rectal drug administration in adults: how, when, why". Nursing Times. Vol. 112, no. 8, 12–14. Retrieved...

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Intramuscular injection

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a muscle. In medicine, it is one of several methods for parenteral administration of medications. Intramuscular injection may be preferred because muscles...

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