Dyneins are a family of cytoskeletal motor proteins that move along microtubules in cells. They convert the chemical energy stored in ATP to mechanical work. Dynein transports various cellular cargos, provides forces and displacements important in mitosis, and drives the beat of eukaryotic cilia and flagella. All of these functions rely on dynein's ability to move towards the minus-end of the microtubules, known as retrograde transport; thus, they are called "minus-end directed motors". In contrast, most kinesin motor proteins move toward the microtubules' plus-end, in what is called anterograde transport.
Dyneins are a family of cytoskeletal motor proteins that move along microtubules in cells. They convert the chemical energy stored in ATP to mechanical...
kidney diseases. Dynein deficiencies can lead to chronic infections of the respiratory tract as cilia fail to function without dynein. Numerous myosin...
Dynein ATPase (EC 3.6.4.2, dynein adenosine 5'-triphosphatase) is an enzyme with systematic name ATP phosphohydrolase (tubulin-translocating). This enzyme...
associated components that enable motility including the outer and inner dynein arms, and radial spokes. Some motile cilia lack the central pair, and some...
nine microtubule doublets with no central microtubule singlets, and no dynein arms on the outer doublets. This arrangement is known as the 9+0 axoneme...
respect to one another; otherwise, vesicular transport proteins such as dynein would dissolve the whole structure. Sorting nexin Walter F., PhD. Boron...
complex that acts as a co-factor for the microtubule motor cytoplasmic dynein-1. It is built around a short filament of actin related protein-1 (Arp1)...
submembranous cortical layers and bundles. Motor proteins of microtubules, dynein and kinesin, and myosin of actin filaments, provide dynamic character of...
provide the main cytoskeletal "tracks" for transportation. Kinesin and dynein are motor proteins that move cargoes in the anterograde (forwards from the...
Dynein axonemal intermediate chain 1 is a protein that in humans is encoded by the DNAI1 gene. The inner- and outer-arm dyneins, which bridge between...
Dynein axonemal light chain 1, (LC1) is a protein that in humans is encoded by the DNAL1 gene. LC1 is a component of outer dynein arms, which contain...
Dynein light chain 1, cytoplasmic is a protein that in humans is encoded by the DYNLL1 gene. Cytoplasmic dyneins are large enzyme complexes with a molecular...
motor protein dynein in a pH-dependent manner. The dynein-regulatory protein, dynactin, was found to play a clear role in regulating the dynein-adenovirus...
the presence of a resistance to the microtubule sliding generated by dynein. Dyneins on the two sides of the central pair apparatus are regulated in an...
vesicles and organelles. This process is propelled by motor proteins such as dynein. Motor proteins connect the transport vesicles to microtubules and actin...
Dynein axonemal intermediate chain 2 also known as axonemal dynein intermediate chain 2, is a protein that in humans is encoded by the DNAI2 gene. The...
are many proteins that bind to microtubules, including the motor proteins dynein and kinesin, microtubule-severing proteins like katanin, and other proteins...
central pair microtubules and the dynein arms, perhaps in a way that maintains the rhythmic activation of the dynein motors. For example, one of the radial...
University of Pennsylvania involved studies of the ATPase pathway of axonemal dynein. She worked as a postdoctoral researcher at Pennsylvania State University...
cells away from the nucleus along microtubules, in anterograde transport. Dynein produces the axonemal beating of cilia and flagella and also transports...
serve structural functions are motor proteins such as myosin, kinesin, and dynein, which are capable of generating mechanical forces. These proteins are crucial...
nerve cell axon via retrograde transport, as its P protein interacts with dynein, a protein present in the cytoplasm of nerve cells. Once the virus reaches...
ingoing return traffic is provided by dynein. Dynein is minus-end directed. There are many forms of kinesin and dynein motor proteins, and each is thought...
(MTs) of the mitotic spindle. There are also motor proteins, including both dynein and kinesin, which generate forces that move chromosomes during mitosis...
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