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Digoxigenin information


Digoxigenin
Names
IUPAC name
3β,12β,14-Trihydroxy-5β-card-20(22)-enolide
Systematic IUPAC name
4-[(1R,3aS,3bR,5aR,7S,9aS,9bS,11R,11aS)-3a,7,11-Trihydroxy-9a,11a-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-1-yl]furan-2(5H)-one
Identifiers
CAS Number
  • 1672-46-4 checkY
ChEBI
  • CHEBI:42098 checkY
ChEMBL
  • ChEMBL1153 checkY
ChemSpider
  • 14728 checkY
ECHA InfoCard 100.015.279 Edit this at Wikidata
PubChem CID
  • 15478
UNII
  • NQ1SX9LNAU checkY
CompTox Dashboard (EPA)
  • DTXSID6051778 Edit this at Wikidata
InChI
  • InChI=1S/C23H34O5/c1-21-7-5-15(24)10-14(21)3-4-17-18(21)11-19(25)22(2)16(6-8-23(17,22)27)13-9-20(26)28-12-13/h9,14-19,24-25,27H,3-8,10-12H2,1-2H3/t14-,15+,16-,17-,18+,19-,21+,22+,23+/m1/s1 checkY
    Key: SHIBSTMRCDJXLN-KCZCNTNESA-N checkY
  • InChI=1/C23H34O5/c1-21-7-5-15(24)10-14(21)3-4-17-18(21)11-19(25)22(2)16(6-8-23(17,22)27)13-9-20(26)28-12-13/h9,14-19,24-25,27H,3-8,10-12H2,1-2H3/t14-,15+,16-,17-,18+,19-,21+,22+,23+/m1/s1
    Key: SHIBSTMRCDJXLN-KCZCNTNEBN
Properties
Chemical formula
C23H34O5
Molar mass 390.51 g/mol
log P 2.57510[1]
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references

Digoxigenin (DIG) is a steroid found exclusively in the flowers and leaves of the plants Digitalis purpurea, Digitalis orientalis and Digitalis lanata (foxgloves), where it is attached to sugars, to form the glycosides (e.g. digoxin, lanatoside C).[2]

  1. ^ "Digoxigenin". Material Data Safety Sheet. ChemSrc.
  2. ^ Polya G (2003). Biochemical Targets of Plant Bioactive Compounds. New York: CRC Press. ISBN 978-0-415-30829-8.

and 24 Related for: Digoxigenin information

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Digoxigenin

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Digoxigenin (DIG) is a steroid found exclusively in the flowers and leaves of the plants Digitalis purpurea, Digitalis orientalis and Digitalis lanata...

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In situ hybridization

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labeled with either radio-, fluorescent- or antigen-labeled bases (e.g., digoxigenin) is localized and quantified in the tissue using either autoradiography...

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Aglycone

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Chemical structures of digoxin (top) and its aglycone digoxigenin (bottom)...

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Digitalis

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exercise. Digoxigenin (DIG) is a steroid found in the flowers and leaves of Digitalis species, and is extracted from D. lanata. Digoxigenin can be used...

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Digitalis lanata

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activity, with five different aglyconees digitoxigenin, gitoxigenin, digoxigenin, diginatigenin and gitaloxigenin in the leaves act as a protection against...

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Hybridization probe

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phosphorus incorporated into the phosphodiester bond in the probe DNA), digoxigenin, a non-radioactive, antibody-based marker, biotin or fluorescein. DNA...

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Molecular probe

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the presence of a complementary sequence by molecular hybridization. Digoxigenin ANS Porphyrin BODIPY Cyanine Hybridization probe "Cancerweb Molecular...

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Chromogenic in situ hybridization

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fluorescence microscope, whereas CISH probes are labelled with biotin or digoxigenin and can be detected using a bright-field microscope after other treatment...

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Cardenolide

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include: acetyldigitoxins acetyldigoxins cymarine digitoxin digitoxigenin digoxigenin digoxin medigoxin neoconvalloside ouabain strophanthidin Bufadienolide...

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Digoxin

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ISBN 3-13-368515-5. Lanatoside C (isolanid, Cedilanid – four glycoside analog), Digoxigenin (aglycone analog) Goldberger ZD, Alexander GC (January 2014). "Digitalis...

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Clostridium botulinum

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monoclonal antibodies. An enzyme-linked immunosorbent assay (ELISA) with digoxigenin-labeled antibodies can also be used to detect the toxin, and quantitative...

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Fluorescein

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antibodies using immunohistochemistry. The latter is a common alternative to digoxigenin, and the two are used together for labelling two genes in one sample...

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Hapten

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used in molecular biology applications include fluorescein, biotin, digoxigenin, and dinitrophenol. Antibodies have successfully been raised against...

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Gene expression

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potentially dangerous, alternative labeling and detection methods, such as digoxigenin and biotin chemistries, have been developed. Perceived disadvantages...

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C23H34O5

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C23H34O5 (molar mass: 390.51 g/mol, exact mass: 390.2406 u) may refer to: Digoxigenin (DIG) Mevastatin, or compactin Treprostinil This set index page lists...

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Lanatoside C

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(glucose, 3-acetyldigitoxose and two digitoxoses) and an aglycon named digoxigenin. Lypka A, Lazowski J (September 1979). "[Comparative study of blood serum...

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Macrophomina phaseolina

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have also recently created species-specific oligonucleotide primers and digoxigenin-labeled probes in hopes of better identifying and detecting M. phaseolina...

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Molecular cytogenetics

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from a tumour sample and biotin is attached. Another labelling protein, digoxigenin, is attached to the reference DNA sample. The labelled DNA samples are...

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Tethered particle motion

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antibody or other reactive molecule (such as anti-digoxigenin) that will bind to an antigen (digoxigenin) at one end of the polymer. After an incubation...

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Digitalis ciliata

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known for. These common glycosides include digitoxigenin, gitoxigenin, digoxigenin, gitaloxigenin, and diginatigenin. The seeds of D. ciliata are rich in...

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Hybridization assay

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similar to a detection probe in that it is labelled with, for example, digoxigenin for downstream signalling. Stringent, low/no salt wash will remove un-ligated...

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Neuronal lineage marker

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correlate it with behavioral manipulations. Some examples are the use of, digoxigenin- or fluorophore-conjugated oligo- nucleotide probes, for the detection...

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ENTPD2

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tissues from C3H/HeSlc strain mice. For ENTPD2 (Entpd2) mRNA analysis, digoxigenin-labeled riboprobes were prepared using a DIG RNA labeling kit. Notably...

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Cherry mottle leaf virus

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Upton, C. (1999). Specific Detection of Cherry Mottle Leaf Virus Using Digoxigenin-Labeled cDNA Probes and RT-PCR. Plant Disease, 83(3), 235–239. doi:10...

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