Diffuse infantile fibromatosis is a rare condition affecting infants during the first three years of life. This condition is a multicentric infiltration of muscle fibers with fibroblasts resembling those seen in aponeurotic fibromas, presenting as lesions and tumors confined usually to the muscles of the arms, neck, and shoulder area[1]: 607 Diffuse infantile fibromatosis is characterized by fast growing benign tumors.[2] This disorder is known to be caused by mutations in germline variants, PDGFRB and NOTCH3, which may be generationally-inherited through autosomal dominant and recessive traits.[3] Although diffuse infantile fibromatosis is classified as benign, it can still lead to life-threatening complications and damage other organs.
^James W, Berger T, Elston D (2005). Andrews' Diseases of the Skin: Clinical Dermatology (10th ed.). Saunders. ISBN 0-7216-2921-0.
^Cite error: The named reference Kameda_1978 was invoked but never defined (see the help page).
^Cite error: The named reference NORD_2020 was invoked but never defined (see the help page).
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Diffuseinfantilefibromatosis is a rare condition affecting infants during the first three years of life. This condition is a multicentric infiltration...
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combination of both. Female-pattern hair loss (FPHL) typically presents as a diffuse thinning of the hair across the entire scalp. Genetic research has identified...
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