This article is about decongestant medications. For their nasal delivery system, see inhaler.
A decongestant, or nasal decongestant, is a type of pharmaceutical drug that is used to relieve nasal congestion in the upper respiratory tract. The active ingredient in most decongestants is either pseudoephedrine or phenylephrine (the latter of which has disputed effectiveness). Intranasal corticosteroids can also be used as decongestants and antihistamines can be used to alleviate runny nose, nasal itch, and sneezing.[1]
Topical decongestants on topical application as dilute solution (0.05–0.1%) produce local vasoconstriction.
Regular use of decongestants for long periods should be avoided because mucosal ciliary function is impaired: atrophic rhinitis and anosmia (loss of the sense of smell) can occur due to persistent vasoconstriction.
Decongestants can be absorbed from the nose via an inhaler and produce systemic effects, mainly central nervous system stimulation and rise in blood pressure. These drugs should be used cautiously in hypertensives and in those receiving monoamine oxidase inhibitors (MAOIs), as they can cause hypertensive crisis.
Expectorants such as guaifenesin are a related type of drug which help to clear mucus.
^Robert D. Ficalora (28 May 2013). Mayo Clinic Internal Medicine Board Review. Oxford University Press. pp. 579–. ISBN 978-0-19-998589-0.
A decongestant, or nasal decongestant, is a type of pharmaceutical drug that is used to relieve nasal congestion in the upper respiratory tract. The active...
Phenylephrine is a medication used as a decongestant for uncomplicated nasal congestion, used to dilate the pupil, used to increase blood pressure (given...
Topical decongestants are decongestants applied directly to the nasal cavity. Their effectiveness by themselves in the common cold appears to have a small...
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name Benzedrex, is an alkylamine primarily utilized as a topical nasal decongestant. Its main indications are relief of congestion due to colds, allergies...
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trial-verified evidence that they have a measurable effect on symptoms. Decongestant nasal sprays are available over-the-counter in many countries. They work...
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available as an over-the-counter (OTC) drug for use as an inhaled nasal decongestant in the United States. Internationally, the production, distribution,...
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sympathomimetic agent and vasoconstrictor which was formerly used as a nasal decongestant. It has also been used as a stimulant. Tuaminoheptane has been found...
pulmonary artery Penis enlargement Phenylephrine, a common over-the-counter decongestant Phenytoin equivalent, used to measure doses of fosphenytoin Physical...
methamphetamine from ephedrine or pseudoephedrine (recovered from nasal decongestant pills). Henri A. Favre; Warren H. Powell, eds. (2014). Nomenclature of...
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encompasses a broad array of drugs, including analgesics, antihistamines and decongestants, among many others. It also includes drugs which are marketed as cough...
drowsiness. Other decongestants such as pseudoephedrine appear effective in adults. Combined oral analgesics, antihistaminics and decongestants are generally...
dilation. Medications that cause vasoconstriction include: antihistamines, decongestants, and stimulants. Severe vasoconstriction may result in symptoms of intermittent...