Loratadine, sold under the brand name Claritin among others, is a medication used to treat allergies.[5] This includes allergic rhinitis (hay fever) and hives.[5] It is also available in drug combinations such as loratadine/pseudoephedrine, in which it is combined with pseudoephedrine, a nasal decongestant.[5] It is taken orally.[5]
Common side effects include sleepiness, dry mouth, and headache.[5] Serious side effects are rare and include allergic reactions, seizures, and liver problems.[6] Use during pregnancy appears to be safe but has not been well studied.[7] It is not recommended in children less than two years old.[6] It is in the second-generation antihistamine family of medication.[5]
Loratadine was patented in 1980 and came to market in 1988.[8] It is on the World Health Organization's List of Essential Medicines.[9] Loratadine is available as a generic medication.[5][10] In the United States, it is available over the counter.[5] In 2021, it was the 67th most commonly prescribed medication in the United States, with more than 9million prescriptions.[11][12]
^"Loratadine Use During Pregnancy". Drugs.com. 10 February 2020. Retrieved 10 April 2020.
^"FDA-sourced list of all drugs with black box warnings (Use Download Full Results and View Query links.)". nctr-crs.fda.gov. FDA. Retrieved 22 October 2023.
^"Claritin Allergy Product information". Health Canada. 25 April 2012. Retrieved 7 June 2022.
^"Clarityn Allergy 10mg Tablets (P & GSL) - Patient Information Leaflet (PIL)". (emc). 30 August 2019. Archived from the original on 10 April 2020. Retrieved 10 April 2020.
^ abcdefgh"Loratadine". The American Society of Health-System Pharmacists. Archived from the original on 21 December 2016. Retrieved 8 December 2016.
^ ab"Clarityn Allergy 10mg Tablets (P) - Summary of Product Characteristics (SmPC) - (eMC)". www.medicines.org.uk. 7 October 2015. Archived from the original on 20 December 2016. Retrieved 13 December 2016.
^"Loratadine Use During Pregnancy". www.drugs.com. Archived from the original on 21 December 2016. Retrieved 13 December 2016.
^Fischer J, Ganellin CR (2006). Analogue-based Drug Discovery. John Wiley & Sons. p. 549. ISBN 9783527607495.
^World Health Organization (2019). World Health Organization model list of essential medicines: 21st list 2019. Geneva: World Health Organization. hdl:10665/325771. WHO/MVP/EMP/IAU/2019.06. License: CC BY-NC-SA 3.0 IGO.
^"Competitive Generic Therapy Approvals". U.S. Food and Drug Administration (FDA). 3 March 2023. Retrieved 6 March 2023.
^"The Top 300 of 2021". ClinCalc. Retrieved 14 January 2024.
^"Loratadine - Drug Usage Statistics". ClinCalc. Retrieved 14 January 2024.
Loratadine, sold under the brand name Claritin among others, is a medication used to treat allergies. This includes allergic rhinitis (hay fever) and hives...
agonist that is used to treat allergies. It is an active metabolite of loratadine. It was patented in 1984 and came into medical use in 2001. Desloratadine...
Schering-Plough and Merck sought permission to market a combined tablet with loratadine and montelukast. However, the FDA has found no benefit from a combined...
maprotiline were first developed in the 1970s as tetracyclic antidepressants. Loratadine was introduced as a non-sedating second generation antihistamine in the...
histamine-induced wheal and flare to a significantly greater degree than loratadine or desloratadine, but was slightly less effective than levocetirizine...
jurisdictions for over-the-counter use Pseudoephedrine/loratadine (Claritin-D) – also an antihistamine via loratadine Amphetamine (formerly sold as Benzedrine, now...
be placed on the market as a safe replacement for the original drug. Loratadine, another non-sedating antihistamine, is the prodrug of desloratadine,...
between the effects of phenylephrine or a placebo. Pseudoephedrine and loratadine–montelukast therapy were found to be significantly more effective than...
an example, "Children's Dimetapp ND" is a 10 mg orally disintegrating loratadine tablet with a "cool blast" flavour additive. The same product with a "Citrus...
been manufactured for sale in the US since 2008. Unlike cetirizine or loratadine, for which the standard dose is one tablet per day, a single acrivastine...
pharmaceutical company. It was patented in 1967. It has been succeeded by both loratadine and desloratadine.: 53 and marketing approvals have been widely withdrawn...
Second-generation antihistamines that do not cause drowsiness are fexofenadine, and loratadine. Use in pregnancy appears safe, but use during breastfeeding is not recommended...
effectiveness but second generation antihistamines such as ketotifen and loratadine have shown equal results with fewer side effects. It is also used as a...
antihistamines, with the second generation antihistamines such as fexofenadine, loratadine and cetirizine being preferred due to less risk of sedation and cognitive...
Zhou Y, Ping Y, Tian S, Li G, Cui Y, Zheng B (2019). "The combination of loratadine with famotidine to relieve the symptoms of urinary frequency in female...
(December 2005). "Meta-analysis of the efficacy of ebastine 20 mg compared to loratadine 10 mg and placebo in the symptomatic treatment of seasonal allergic rhinitis"...
postoperative nausea and vomiting. Nonsedating antihistamines such as loratadine Nasal sprays containing decongestants or steroids The SUSMP March 2018...
drugs, including the natural antibiotic vancomycin, the antihistamine loratadine (Claritin), the antidepressant sertraline (Zoloft), the anti-epileptic...
H1-antihistamines, such as cetirizine or ketotifen or fexofenadine or loratadine H2-antihistamines, such as ranitidine or famotidine Antileukotrienes,...
ordinary urticaria and healthy controls: diurnal variation, influence of loratadine and prednisolone and relationship to disease activity". Clinical and Experimental...
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