A cutaneous myxoma, or superficial angiomyxoma, consists of a multilobulated myxoid mass containing stellate or spindled fibroblasts with pools of mucin forming cleft-like spaces. There is often a proliferation of blood vessels and an inflammatory infiltrate. Staining is positive for vimentin, negative for cytokeratin and desmin, and variable for CD34, Factor VIIIa, SMA, MSA and S-100.[1]
Clinically, it may present as solitary or multiple flesh-colored nodules on the face, trunk, or extremities. It may occur as part of the Carney complex, and is sometimes the first sign. Local recurrence is common.[2] Cutaneous myxoma is diagnosed based on histopathological features. The differential diagnosis for cutaneous myxoma include alopecia areata, verrucous hamartoma, cyst, fibroma, glioma, hemangioma, lipoma, scar, and nevus sebaceous. Treatment involves complete surgical excision.
^Satter EK (October 2009). "Solitary superficial angiomyxoma: an infrequent but distinct soft tissue tumor". J. Cutan. Pathol. 36 (Suppl 1): 56–9. doi:10.1111/j.1600-0560.2008.01216.x. PMID 19187115. S2CID 1528140. Archived from the original on 2012-12-10.
^James, William; Berger, Timothy; Elston, Dirk (2005). Andrews' Diseases of the Skin: Clinical Dermatology (10th ed.). Saunders. p. 614. ISBN 0-7216-2921-0.
A cutaneousmyxoma, or superficial angiomyxoma, consists of a multilobulated myxoid mass containing stellate or spindled fibroblasts with pools of mucin...
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lead to retiform purpura include cholesterol emboli, septic emboli, atrial myxoma, or other manifestations like nonbacterial thrombotic endocarditis (marantic...
associated with LAMB (lentigines, atrial myxomas, muco-cutaneousmyxomas, and blue naevi) syndrome, NAME (nevi, atrial myxoma, myxoid neurofibromas, and ephelides)...
in 1983, but the term angiomyxoma dates back to at least 1952. MyxomaCutaneousmyxoma (Superficial angiomyxoma) Mandal S, Dhingra K, Roy S, Khurana N...
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(Sylvilagus bachmani), the common tapeti is a natural reservoir for the myxoma virus. This relationship was discovered by Brazilian physician Henrique...
melanocytic nevi: treatment modalities and management options". Seminars in Cutaneous Medicine and Surgery. 26 (4): 231–240. doi:10.1016/j.sder.2008.03.007...
which have been seen in association with Gorlin syndrome. However, cardiac myxomas are known to be associated with tuberous sclerosis. The tumor may be seen...